Tuesday, January 31, 2012

Iran vows to stop "some" oil sales as inspectors visit (Reuters)

TEHRAN (Reuters) ? Iran sent conflicting signals in a dispute with the West over its nuclear ambitions, vowing to stop oil exports soon to "some" countries but postponing a parliamentary debate on a proposed halt to crude sales to the European Union.

The Islamic Republic declared itself optimistic about a visit by U.N. nuclear experts that began Sunday but also warned the inspectors to be "professional" or see Tehran reducing cooperation with the world body on atomic matters.

Lawmakers have raised the possibility of turning the tables on the EU which will implement its own embargo on Iranian oil by July as it tightens sanctions on Tehran over the nuclear program.

But India, the world's fourth-largest oil consumer, said it would not take steps to cut petroleum imports from Iran despite U.S. and European sanctions against Tehran.

The International Atomic Energy Agency (IAEA) inspection delegation will try to advance efforts to resolve a row about the nuclear work which Iran says is purely civilian but the West suspects is aimed at seeking a nuclear weapon.

Tension with the West rose this month when Washington and the EU imposed the toughest sanctions yet in a drive to force Tehran to provide more information on its nuclear program. The measures take direct aim at the ability of OPEC's second biggest Oil exporter to sell its crude.

In a remark suggesting Iran would fight sanctions with sanctions, Iran's oil minister said the Islamic state would soon stop exporting crude to "some" countries.

Rostam Qasemi did not identify the countries but was speaking less than a week after the EU's 27 member states agreed to stop importing crude from Iran from July 1.

"Soon we will cut exporting oil to some countries," the state news agency IRNA quoted Qasemi as saying.

India, a major customer for Iranian crude, made clear it would not join the wider international efforts to put pressure on Tehran by cutting oil purchases.

"It is not possible for India to take any decision to reduce the imports from Iran drastically, because among the countries which can provide the requirement of the emerging economies, Iran is an important country amongst them," Finance Minister Pranab Mukherjee told reporters on a visit to the Unites States.

The United States wants buyers in Asia, Iran's biggest oil market, to cut imports to put further pressure on Tehran.

DISCUSSION POSTPONED

Iranian lawmakers had been due to debate a bill Sunday that could have cut off oil supplies to the EU in days, in a move calculated to hit ailing European economies before the EU-wide ban on took effect.

But Iranian MPs postponed discussing the measure.

"No such draft bill has yet been drawn up and nothing has been submitted to the parliament. What exists is a notion by the deputies which is being seriously pursued to bring it to a conclusive end," Emad Hosseini, spokesman for parliament's Energy Committee, told Mehr news agency.

Iranian officials say sanctions have had no impact on the country. "Iranian oil has its own market, even if we cut our exports to Europe," Oil Minister Qasemi said.

Another lawmaker said the bill would oblige the government to cut Iran's oil supplies to the EU for five to 15 years, the semi-official Fars news agency reported.

By turning the sanctions back on the EU, lawmakers hope to deny the bloc a six-month window it had planned to give those of its members most dependent on Iranian oil - including some of the most economically fragile in southern Europe - to adapt.

NUCLEAR WATCHDOG

Before departing from Vienna, IAEA Deputy Director General Herman Nackaerts said he hoped Iran would tackle the watchdog's concerns "regarding the possible military dimensions of Iran's nuclear program."

Mehr quoted Foreign Minister Ali Akbar Salehi as saying during a trip to Ethiopia: "We are very optimistic about the outcome of the IAEA delegation's visit to Iran ... Their questions will be answered during this visit."

"We have nothing to hide and Iran has no clandestine (nuclear) activities."

Striking a sterner tone, Iran's parliament speaker, Ali Larijani, warned the IAEA team to carry out a "logical, professional and technical" job or suffer the consequences.

"This visit is a test for the IAEA. The route for further cooperation will be open if the team carries out its duties professionally," said Larijani, state media reported.

"Otherwise, if the IAEA turns into a tool (for major powers to pressure Iran), then Iran will have no choice but to consider a new framework in its ties with the agency."

Iran's parliament has approved bills in the past to oblige the government to review its level of cooperation with the IAEA. However, Iran's top officials have always underlined the importance of preserving ties with the watchdog body.

The head of the state-run National Iranian Oil Company (NIOC) said late Saturday that the export embargo would hit European refiners, such as Italy's Eni, that are owed oil from Iran as part of long-standing buy-back contracts under which they take payment for past oilfield projects in crude.

The EU accounted for 25 percent of Iranian crude oil sales in the third quarter of 2011. However, analysts say the global oil market will not be overly disrupted if parliament votes for the bill that would turn off the oil tap for Europe.

Potentially more disruptive to the world oil market and global security is the risk of Iran's standoff with the West escalating into military conflict.

Iran has repeatedly said it could close the vital Strait of Hormuz shipping lane if sanctions succeed in preventing it from exporting crude, a move Washington said it would not tolerate.

(Additional reporting by Hashem Kalantari, Robin Pomeroy and Hossein Jaseb in Tehran, Svetlana Kovalyova in Milan and Fredrik Dahl in Vienna; Writing by Parisa Hafezi and Robin Pomeroy; Editing by William Maclean and David Stamp)

Source: http://us.rd.yahoo.com/dailynews/rss/iran/*http%3A//news.yahoo.com/s/nm/20120130/wl_nm/us_iran

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Astronomers solve mystery of vanishing electrons in Earth's outer radiation belt

ScienceDaily (Jan. 29, 2012) ? UCLA researchers have explained the puzzling disappearing act of energetic electrons in Earth's outer radiation belt, using data collected from a fleet of orbiting spacecraft.

In a paper published Jan. 29 in the advance online edition of the journal Nature Physics, the team shows that the missing electrons are swept away from the planet by a tide of solar wind particles during periods of heightened solar activity.

"This is an important milestone in understanding Earth's space environment," said lead study author Drew Turner, an assistant researcher in the UCLA Department of Earth and Space Sciences and a member of UCLA's Institute for Geophysics and Planetary Physics (IGPP). "We are one step closer towards understanding and predicting space weather phenomena."

During powerful solar events such as coronal mass ejections, parts of the magnetized outer layers of sun's atmosphere crash onto Earth's magnetic field, triggering geomagnetic storms capable of damaging the electronics of orbiting spacecraft. These cosmic squalls have a peculiar effect on Earth's outer radiation belt, a doughnut-shaped region of space filled with electrons so energetic that they move at nearly the speed of light.

"During the onset of a geomagnetic storm, nearly all the electrons trapped within the radiation belt vanish, only to come back with a vengeance a few hours later," said Vassilis Angelopoulos, a UCLA professor of Earth and space sciences and IGPP researcher.

The missing electrons surprised scientists when the trend was first measured in the 1960s by instruments onboard the earliest spacecraft sent into orbit, said study co-author Yuri Shprits, a research geophysicist with the IGPP and the departments of Earth and space sciences, and atmospheric and oceanic sciences.

"It's a puzzling effect," he said. "Oceans on Earth do not suddenly lose most of their water, yet radiation belts filled with electrons can be rapidly depopulated."

Even stranger, the electrons go missing during the peak of a geomagnetic storm, a time when one might expect the radiation belt to be filled with energetic particles because of the extreme bombardment by the solar wind.

Where do the electrons go? This question has remained unresolved since the early 1960s. Some believed the electrons were lost to Earth's atmosphere, while others hypothesized that the electrons were not permanently lost at all but merely temporarily drained of energy so that they appeared absent.

"Our study in 2006 suggested that electrons may be, in fact, lost to the interplanetary medium and decelerated by moving outwards," Shprits said. "However, until recently, there was no definitive proof for this theory."

To resolve the mystery, Turner and his team used data from three networks of orbiting spacecraft positioned at different distances from Earth to catch the escaping electrons in the act. The data show that while a small amount of the missing energetic electrons did fall into the atmosphere, the vast majority were pushed away from the planet, stripped away from the radiation belt by the onslaught of solar wind particles during the heightened solar activity that generated the magnetic storm itself.

A greater understanding of Earth's radiation belts is vital for protecting the satellites we rely on for global positioning, communications and weather monitoring, Turner said. Earth's outer radiation belt is a harsh radiation environment for spacecraft and astronauts; the high-energy electrons can penetrate a spacecraft's shielding and wreak havoc on its delicate electronics. Geomagnetic storms triggered when the oncoming particles smash into Earth's magnetosphere can cause partial or total spacecraft failure.

"While most satellites are designed with some level of radiation protection in mind, spacecraft engineers must rely on approximations and statistics because they lack the data needed to model and predict the behavior of high-energy electrons in the outer radiation belt," Turner said.

During the 2003 "Halloween Storm," more than 30 satellites reported malfunctions, and one was a total loss, said Angelopoulos, a co-author of the current research. As the solar maximum approaches in 2013, marking the sun's peak activity over a roughly 11-year cycle, geomagnetic storms may occur as often as several times per month.

"High-energy electrons can cut down the lifetime of a spacecraft significantly," Turner said. "Satellites that spend a prolonged period within the active radiation belt might stop functioning years early."

While a mechanized spacecraft might include multiple redundant circuits to reduce the risk of total failure during a solar event, human explorers in orbit do not have the same luxury. High-energy electrons can punch through astronauts' spacesuits and pose serious health risks, Turner said.

"As a society, we've become incredibly dependent on space-based technology," he said. "Understanding this population of energetic electrons and their extreme variations will help create more accurate models to predict the effect of geomagnetic storms on the radiation belts."

Key observational data used in this study was collected by a network of NASA spacecraft known as THEMIS (Time History of Events and Macroscale Interactions during Substorms); Angelopoulos is the principal investigator of the THEMIS mission. Additional information was obtained from two groups of weather satellites called POES (Polar Operational Environmental Satellite) and GOES (Geostationary Operational Environmental Satellite).

A new collaboration between UCLA and Russia's Moscow State University promises to paint an even clearer picture of these vanishing electrons. Slated for launch in the spring of 2012, the Lomonosov spacecraft will fly in low Earth orbit to measure highly energetic particles with unprecedented accuracy, said Shprits, the principal investigator of the project. Several key instruments for the mission are being developed and assembled at UCLA.

Earth's radiation belts were discovered in 1958 by Explorer I, the first U.S. satellite that traveled to space.

"What we are studying was the first discovery of the space age," Shprits said. "People realized that launches of spacecraft didn't only make the news, they could also make scientific discoveries that were completely unexpected."

This project received federal funding from NASA and the National Science Foundation. Other co-authors include Michael Hartinger, a UCLA graduate student in Earth and space sciences.

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Story Source:

The above story is reprinted from materials provided by University of California - Los Angeles. The original article was written by Kim DeRose.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Drew L. Turner, Yuri Shprits, Michael Hartinger, Vassilis Angelopoulos. Explaining sudden losses of outer radiation belt electrons during geomagnetic storms. Nature Physics, 2012; DOI: 10.1038/nphys2185

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/01/120129150958.htm

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Monday, January 30, 2012

DNDi and Abbott expand partnership to boost innovation for neglected tropical diseases

DNDi and Abbott expand partnership to boost innovation for neglected tropical diseases [ Back to EurekAlert! ] Public release date: 30-Jan-2012
[ | E-mail | Share Share ]

Contact: Violaine Dallenbach
vdallenbach@dndi.org
41-229-069-247
Drugs for Neglected Diseases Initiative

Geneva, Switzerland -- The Drugs for Neglected Diseases initiative (DNDi) and Abbott have signed a four-year joint research and non-exclusive licensing agreement to undertake research on new treatments for several of the world's most neglected tropical diseases, including Chagas disease, helminth infections, leishmaniasis and sleeping sickness. Through this collaboration, DNDi and Abbott scientists will focus initial efforts on discovering and advancing novel antimicrobial agents with activity against these neglected diseases.

Since 2009, Abbott has provided compounds for DNDi to screen for activity against neglected diseases. This new agreement expands this relationship, and provides DNDi access to selected classes of molecules and accompanying data generated by Abbott that are crucial for the development of effective and accessible new treatments for neglected diseases.

"Innovative product development partnerships have significant potential for addressing neglected diseases," said

Dr. John Leonard, senior vice president, Pharmaceuticals, Research and Development, Abbott. "By combining the unique scientific expertise and resources of DNDi and Abbott, we look forward to accelerating research to find practical new treatment options for people affected by these diseases."

"Abbott has demonstrated a great level of commitment by partnering with DNDi to share not only its compounds, but also its expertise and resources. For DNDi, this implies a new critical mass of knowledge to pursue our goals of addressing the unmet needs of neglected patients in the poorest areas of the world," said Dr Bernard Pcoul, Executive Director of DNDi.

Equitable access to treatments for neglected diseases in all endemic countries, not only least-developed countries, is at the core of this agreement, and DNDi has committed to ensuring the lowest sustainable pricing for any products developed and distributed as a result of the agreement. Intellectual property (IP) related to this agreement, existing relevant Abbott IP and new IP generated by this collaboration will be subject to a principle of non-exclusive licensing to address neglected diseases in endemic countries. Under the agreement, Abbott has the right of first negotiation to become DNDi's development and distribution partner. DNDi is free to engage other partners if Abbott chooses not to serve as a development and distribution partner.

The agreement, in short implies:

  • Both DNDi and Abbott share their unique scientific expertise and resources to advance the development of drugs adapted to patient needs.
  • DNDi gains access to Abbott compounds, data and information to accelerate drug development.
  • Non-exclusive licensing structure for relevant IP in the neglected diseases field provides flexibility, thus expanding the potential of drug development.
  • Any resulting products will be provided in endemic countries at the lowest sustainable price to expand patient access.

###

For more information please contact:

Violaine Dallenbach
Press and Communication Manager, DNDi
vdallenbach@dndi.org
Tel: 41-22-906-92-47

Colin McBean
Abbott
colin.mcbean@abbott.com
Tel: 847-938-3083

About the London NTD event

The commitments announced by DNDi are a key part of a new, coordinated push by a diverse range of public and private partners to combat 10 Neglected Tropical Diseases (NTDs) by 2020. Today, 13 pharmaceutical companies, the U.S. and U.K. governments, the Bill & Melinda Gates Foundation, the World Bank and officials from NTD-endemic countries pledged to bring a unique focus to defeating these diseases and to work together to improve the lives of the billion people worldwide affected by NTDs.

In the largest coordinated effort to date to combat NTDs, the group announced at an event at the Royal College of Physicians that they would: sustain or expand existing drug donation programs to meet demand through 2020; share expertise and compounds to accelerate research and development of new drugs; and provide more than US$785 million to support R&D efforts and strengthen drug distribution and implementation programmes. The partners also signed onto the "London Declaration on Neglected Tropical Diseases," in which they pledged new levels of collaboration and tracking and reporting of progress.

New funding commitments will fully support work toward the eradication of Guinea worm, as well as expedite progress toward the 2020 goals of: elimination for lymphatic filariasis, blinding trachoma, sleeping sickness and leprosy; and control of soil-transmitted helminthes, schistosomiasis, river blindness, Chagas and visceral leishmaniasis.

About Neglected Tropical Diseases

Neglected diseases are a group of tropical infections that disproportionately affect the world's poor and marginalized populations. According to the World Health Organization (WHO), more than a billion people or one-sixth of the global population suffer from one or more tropical infectious diseases. The partnership between DNDi and Abbott is focused on finding new treatments to address the following diseases:

  • Chagas disease is endemic in 21 countries across Latin America and kills more people in the region than any other parasite-borne disease, including malaria. In total, 100 million people are at risk worldwide and patient numbers are growing in non-endemic countries such as the United States, Australia, and Europe. The disease is transmitted by an insect known as the "kissing bug" and, without treatment, is potentially fatal. Existing treatments have an unsatisfactory cure rate and can have toxic side effects.
  • Helminth infections include filarial diseases, onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) caused by parasitic worms, which inflict the heaviest socioeconomic burden of all the neglected tropical diseases and affect millions in poverty-stricken areas. Current treatments for these diseases cannot be used for patients who are infected with a related nematode worm, Loa loa, because of the severe side effects caused by rapid killing of juvenile Loa loa worms. There is an urgent need for a new treatment for onchocerciasis and lymphatic filariasis in Loa loa endemic regions.
  • Leishmaniasis occurs in 98 countries, placing 350 million people at risk worldwide. The parasite that leads to infection is called Leishmania and transmitted by sandflies. Leishmaniasis is a poverty-associated disease with several different forms. Visceral leismaniasis, which is fatal without treatment, and cutaneous leshmaniasis are the most common. Existing treatments are difficult to administer, toxic, and costly. Drug resistance also is an increasing problem.
  • Sleeping sickness, or Human African Trypanosomiasis (HAT), is endemic in 36 African countries and around 60 million people are at risk of being infected. HAT is transmitted by the tsetse fly and is fatal without treatment. Up until 2009, existing treatments for stage 2 of the disease were toxic or difficult to administer. In 2009, DNDi and its partners launched the first new treatment for HAT in 25 years.

    About Drugs for Neglected Diseases initiative (DNDi)

    The Drugs for Neglected Diseases initiative (DNDi) is a not-for-profit research and development organization working to deliver new treatments for neglected diseases, in particular sleeping sickness (human African trypanosomiasis), Chagas disease, leishmaniasis, specific helminth infections, paediatric HIV, and malaria. DNDi was established in 2003 by Mdecins Sans Frontires/Doctors Without Borders (MSF), Oswaldo Cruz Foundation (FIOCRUZ) from Brazil, Indian Council for Medical Research (ICMR), Kenya Medical Research Institute (KEMRI), Ministry of Health of Malaysia, and Pasteur Institute of France. The Special Programme for Tropical Disease Research (TDR) serves as a permanent observer. Since its inception, DNDi has delivered six new treatments for neglected patients: two fixed-dose antimalarials (ASAQ and ASMQ), nifurtimox-eflornithine combination therapy (NECT) for late-stage sleeping sickness, sodium stibogluconate and paromomycin (SSG&PM) combination therapy for visceral leishmaniasis in Africa, a set of combination therapies for visceral leishmaniasis in Asia, and a paediatric dosage form of benznidazole for Chagas disease. http://www.dndi.org

    About Abbott

    Abbott and its philanthropic foundation, the Abbott Fund, are supporting innovative new efforts to advance the prevention, diagnosis and treatment of neglected diseases around the world. In 2009, Abbott created an Executive Council for Neglected Diseases to coordinate efforts across the company to contribute innovative technologies, drug compounds and scientific expertise, working in partnership with non-profit organizations, academic research institutions and multilateral agencies. The Abbott Fund also supports programs to advance research and expand community education and outreach on neglected diseases.

    Abbott is a global, broad-based health care company devoted to the discovery, development, manufacture and marketing of pharmaceuticals and medical products, including nutritionals, devices and diagnostics. The company employs nearly 90,000 people and markets its products in more than 130 countries. Abbott's news releases and other information are available on the company's website at http://www.abbott.com.



    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


  • DNDi and Abbott expand partnership to boost innovation for neglected tropical diseases [ Back to EurekAlert! ] Public release date: 30-Jan-2012
    [ | E-mail | Share Share ]

    Contact: Violaine Dallenbach
    vdallenbach@dndi.org
    41-229-069-247
    Drugs for Neglected Diseases Initiative

    Geneva, Switzerland -- The Drugs for Neglected Diseases initiative (DNDi) and Abbott have signed a four-year joint research and non-exclusive licensing agreement to undertake research on new treatments for several of the world's most neglected tropical diseases, including Chagas disease, helminth infections, leishmaniasis and sleeping sickness. Through this collaboration, DNDi and Abbott scientists will focus initial efforts on discovering and advancing novel antimicrobial agents with activity against these neglected diseases.

    Since 2009, Abbott has provided compounds for DNDi to screen for activity against neglected diseases. This new agreement expands this relationship, and provides DNDi access to selected classes of molecules and accompanying data generated by Abbott that are crucial for the development of effective and accessible new treatments for neglected diseases.

    "Innovative product development partnerships have significant potential for addressing neglected diseases," said

    Dr. John Leonard, senior vice president, Pharmaceuticals, Research and Development, Abbott. "By combining the unique scientific expertise and resources of DNDi and Abbott, we look forward to accelerating research to find practical new treatment options for people affected by these diseases."

    "Abbott has demonstrated a great level of commitment by partnering with DNDi to share not only its compounds, but also its expertise and resources. For DNDi, this implies a new critical mass of knowledge to pursue our goals of addressing the unmet needs of neglected patients in the poorest areas of the world," said Dr Bernard Pcoul, Executive Director of DNDi.

    Equitable access to treatments for neglected diseases in all endemic countries, not only least-developed countries, is at the core of this agreement, and DNDi has committed to ensuring the lowest sustainable pricing for any products developed and distributed as a result of the agreement. Intellectual property (IP) related to this agreement, existing relevant Abbott IP and new IP generated by this collaboration will be subject to a principle of non-exclusive licensing to address neglected diseases in endemic countries. Under the agreement, Abbott has the right of first negotiation to become DNDi's development and distribution partner. DNDi is free to engage other partners if Abbott chooses not to serve as a development and distribution partner.

    The agreement, in short implies:

    • Both DNDi and Abbott share their unique scientific expertise and resources to advance the development of drugs adapted to patient needs.
    • DNDi gains access to Abbott compounds, data and information to accelerate drug development.
    • Non-exclusive licensing structure for relevant IP in the neglected diseases field provides flexibility, thus expanding the potential of drug development.
    • Any resulting products will be provided in endemic countries at the lowest sustainable price to expand patient access.

    ###

    For more information please contact:

    Violaine Dallenbach
    Press and Communication Manager, DNDi
    vdallenbach@dndi.org
    Tel: 41-22-906-92-47

    Colin McBean
    Abbott
    colin.mcbean@abbott.com
    Tel: 847-938-3083

    About the London NTD event

    The commitments announced by DNDi are a key part of a new, coordinated push by a diverse range of public and private partners to combat 10 Neglected Tropical Diseases (NTDs) by 2020. Today, 13 pharmaceutical companies, the U.S. and U.K. governments, the Bill & Melinda Gates Foundation, the World Bank and officials from NTD-endemic countries pledged to bring a unique focus to defeating these diseases and to work together to improve the lives of the billion people worldwide affected by NTDs.

    In the largest coordinated effort to date to combat NTDs, the group announced at an event at the Royal College of Physicians that they would: sustain or expand existing drug donation programs to meet demand through 2020; share expertise and compounds to accelerate research and development of new drugs; and provide more than US$785 million to support R&D efforts and strengthen drug distribution and implementation programmes. The partners also signed onto the "London Declaration on Neglected Tropical Diseases," in which they pledged new levels of collaboration and tracking and reporting of progress.

    New funding commitments will fully support work toward the eradication of Guinea worm, as well as expedite progress toward the 2020 goals of: elimination for lymphatic filariasis, blinding trachoma, sleeping sickness and leprosy; and control of soil-transmitted helminthes, schistosomiasis, river blindness, Chagas and visceral leishmaniasis.

    About Neglected Tropical Diseases

    Neglected diseases are a group of tropical infections that disproportionately affect the world's poor and marginalized populations. According to the World Health Organization (WHO), more than a billion people or one-sixth of the global population suffer from one or more tropical infectious diseases. The partnership between DNDi and Abbott is focused on finding new treatments to address the following diseases:

  • Chagas disease is endemic in 21 countries across Latin America and kills more people in the region than any other parasite-borne disease, including malaria. In total, 100 million people are at risk worldwide and patient numbers are growing in non-endemic countries such as the United States, Australia, and Europe. The disease is transmitted by an insect known as the "kissing bug" and, without treatment, is potentially fatal. Existing treatments have an unsatisfactory cure rate and can have toxic side effects.
  • Helminth infections include filarial diseases, onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) caused by parasitic worms, which inflict the heaviest socioeconomic burden of all the neglected tropical diseases and affect millions in poverty-stricken areas. Current treatments for these diseases cannot be used for patients who are infected with a related nematode worm, Loa loa, because of the severe side effects caused by rapid killing of juvenile Loa loa worms. There is an urgent need for a new treatment for onchocerciasis and lymphatic filariasis in Loa loa endemic regions.
  • Leishmaniasis occurs in 98 countries, placing 350 million people at risk worldwide. The parasite that leads to infection is called Leishmania and transmitted by sandflies. Leishmaniasis is a poverty-associated disease with several different forms. Visceral leismaniasis, which is fatal without treatment, and cutaneous leshmaniasis are the most common. Existing treatments are difficult to administer, toxic, and costly. Drug resistance also is an increasing problem.
  • Sleeping sickness, or Human African Trypanosomiasis (HAT), is endemic in 36 African countries and around 60 million people are at risk of being infected. HAT is transmitted by the tsetse fly and is fatal without treatment. Up until 2009, existing treatments for stage 2 of the disease were toxic or difficult to administer. In 2009, DNDi and its partners launched the first new treatment for HAT in 25 years.

    About Drugs for Neglected Diseases initiative (DNDi)

    The Drugs for Neglected Diseases initiative (DNDi) is a not-for-profit research and development organization working to deliver new treatments for neglected diseases, in particular sleeping sickness (human African trypanosomiasis), Chagas disease, leishmaniasis, specific helminth infections, paediatric HIV, and malaria. DNDi was established in 2003 by Mdecins Sans Frontires/Doctors Without Borders (MSF), Oswaldo Cruz Foundation (FIOCRUZ) from Brazil, Indian Council for Medical Research (ICMR), Kenya Medical Research Institute (KEMRI), Ministry of Health of Malaysia, and Pasteur Institute of France. The Special Programme for Tropical Disease Research (TDR) serves as a permanent observer. Since its inception, DNDi has delivered six new treatments for neglected patients: two fixed-dose antimalarials (ASAQ and ASMQ), nifurtimox-eflornithine combination therapy (NECT) for late-stage sleeping sickness, sodium stibogluconate and paromomycin (SSG&PM) combination therapy for visceral leishmaniasis in Africa, a set of combination therapies for visceral leishmaniasis in Asia, and a paediatric dosage form of benznidazole for Chagas disease. http://www.dndi.org

    About Abbott

    Abbott and its philanthropic foundation, the Abbott Fund, are supporting innovative new efforts to advance the prevention, diagnosis and treatment of neglected diseases around the world. In 2009, Abbott created an Executive Council for Neglected Diseases to coordinate efforts across the company to contribute innovative technologies, drug compounds and scientific expertise, working in partnership with non-profit organizations, academic research institutions and multilateral agencies. The Abbott Fund also supports programs to advance research and expand community education and outreach on neglected diseases.

    Abbott is a global, broad-based health care company devoted to the discovery, development, manufacture and marketing of pharmaceuticals and medical products, including nutritionals, devices and diagnostics. The company employs nearly 90,000 people and markets its products in more than 130 countries. Abbott's news releases and other information are available on the company's website at http://www.abbott.com.



    [ Back to EurekAlert! ] [ | E-mail | Share Share ]

    ?


    AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


  • Source: http://www.eurekalert.org/pub_releases/2012-01/dfnd-daa012712.php

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    Sunday, January 29, 2012

    Kazakh opposition gathers for rare rally (AP)

    ALMATY, Kazakhstan ? Hundreds of opposition supporters protested the results of recent elections and the violent suppression of an oil workers protest at a demonstrationi Saturday in Kazakhstan's commercial capital.

    The meeting took place peacefully and police did not break it up, as is common at unauthorized political rallies in the former Soviet Central Asian nation.

    However, the All-National Social Democratic Party, or OSDP, said in a statement after the meeting that several party members, including co-leader Zharmakhan Tuyakbay, were detained and taken to the police station.

    OSDP co-leader Bulat Abilov told the crowd in the center of Almaty that meetings would be held once every month. Even the smallest of rallies are a rarity in a nation in which dissent is not tolerated.

    Before the meeting concluded, the crowd united in prayer in commemoration of people killed last month in the western oil town of Zhanaozen, where at least 16 died during clashes between police and striking laborers. Authorities are prosecuting several police officers for exceeding their authority by opening fire on rampaging protesters.

    At the end of the meeting, Abilov led the crowd in chants of "We are sick of this outrage!"

    The ruling Nur Otan party gained control of 83 of the parliament's 107 seats in elections this month that international observers said didn't meet democratic standards.

    OSDP, the only genuinely robust opposition force taking part, garnered 2 percent of the ballot.

    International observers said the election failed to meet democratic standards.

    Kazakhstan, which occupies an area around the size of Western Europe and shares long borders with Russia and China, is viewed as a reliable energy and security partner by the West, but has come under fire for its democratic shortcomings. It is becoming increasingly important as a supplier of oil and gas, and is key to the northern delivery route for supplies to the United States-led military operation in Afghanistan.

    Earlier this week, police arrested the leader of the unregistered Alga party, Vladmir Kozlov, for inciting social unrest in Zhanaozen. The editor of independent newspaper Vzglyad, Igor Sinyavsky, was also jailed and faces charges of "calling for the violent overthrow of the constitutional order."

    An Almaty court Friday ordered the men to be remanded in custody for two months.

    Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20120128/ap_on_re_as/as_kazakhstan_opposition_rally

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    France mulls Afghan move as Karzai visits (AP)

    PARIS ? France's president is expected to announce whether he will order an accelerated pullout of French troops from the NATO-led mission in Afghanistan after a meeting with the Afghan leader.

    Afghan President Hamid Karzai was holding a long-scheduled Paris meeting with Nicolas Sarkozy Friday ? a week after a Taliban infiltrated the Afghan army and shot dead four French troops in eastern Afghanistan.

    Sarkozy's government has been under political pressure to withdraw French troops before the United States' pegged timetable ends in 2014. France holds presidential elections this spring.

    After the shootings, France halted its training programs for the Afghan military and threatened to withdraw its 3,600 troops ahead of schedule ? a move that could pressure NATO.

    Source: http://us.rd.yahoo.com/dailynews/rss/europe/*http%3A//news.yahoo.com/s/ap/20120127/ap_on_re_eu/eu_france_afghanistan

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    Saturday, January 28, 2012

    Watch key testimony on Hasegawa?s Washington Investment Trust bill and an interview with KING 5?s Robert Mak

    WIT Task Force member Darel Grothaus presents testimony on HB 2434 to the House Committee on Business and Financial Services on January 26, 2012:

    If the video doesn?t play, please click here

    King County Assesor Lloyd Hara presents testimony on SB 6310 to the Senate Committee on Financial Institutions, Housing & Insurance on January 25, 2012:

    If the video doesn?t play, please click here

    Watch an interview with Robert Mak on January 25, 2012:

    If the video doesn?t play, please click here

    Source: http://www.housedemocrats.wa.gov/bob-hasegawa/watch-key-testimony-on-hasegawas-washington-investment-trust-bill-and-an-interview-with-king-5%E2%80%99s-robert-mak/

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    Friday, January 27, 2012

    Exit Code:6; Windows XP, SP3

    This is my first time installing PS CS5.1 Master Collection and after everything was finished I got this:

    ?

    How do I fix this issue?

    Exit Code: 6

    ?

    ?

    ?

    ?

    -------------------------------------- Summary --------------------------------------

    ?

    ?

    ?

    ?

    - 0 fatal error(s), 2 error(s), 2 warning(s)

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    WARNING: DW024: The payload: Adobe Photoshop CS5.1 Core? {08EF22BC-43B2-4B4E-BA12-52B18F418F38} requires a UI parent with following specification:

    ?

    ?

    ???? ?????Family: Photoshop

    ?

    ?

    ???? ?????ProductName: Adobe Photoshop CS5.1 Core_x64

    ?

    ?

    ???? ?????This parent relationship is not satisfied, because this payload is not present in this session.

    ?

    ?

    ?

    ?

    ----------- Payload: {CFA46C39-C539-4BE9-9364-495003C714AD} Adobe SwitchBoard 2.0 2.0.0.0 -----------

    ?

    ?

    ?

    ?

    WARNING: DF029: ARKServiceControl::StartService: Service not started/stopped SwitchBoard. Current State: 0 Exit Code: 0 Service Specific Exit Code: 0(Seq 1)

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ?

    ERROR: DW050: The following payload errors were found during install:

    ?

    ?

    ?

    ?

    ERROR: DW050:? - AdobeHelp: Install failed

    ?

    ?

    ?

    ?

    ---------------------------------------------------------------------- ---------------

    ?

    ?

    ?

    ?

    Source: http://forums.adobe.com/thread/955008

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    Casio?s new smartphone looks like an oversized watch; might survive the apocalypse (Yahoo! News)

    It's probably not bullet-resistant, but it may be the closest you'll get

    Looking for the most rugged?smartphone on the planet? Well then, meet the new?Casio ? yes, that Casio ??Android G-Shock. It's the kind of smartphone that?Lewis and Clark would have taken with them had there been 4G cell service in 1804.

    The phone appears to be geared toward the more adventurous smartphone owner ? it's both water-resistant (to 1.0 bar) and pressure-resistant (1.0 ton), so you can take it deep sea diving. It's also shock-resistant to 10 feet, so if your son drops it off the front porch, you're covered. Oh, and did we mention that its thick frame and unusual shape makes it looks?exactly like an oversized watch?

    Cool and stylish as the phone looks from the outside, we really don't know a lot about the inside yet, because Casio's not telling us. All we know is that it'll be running Android. Casio is being hush-hush about the smartphone's processor as well, aside from the fact that it still works even at the bottom of your backyard swimming pool.

    This article was written by Fox Van Allen and originally appeared on Tecca

    More from Tecca:

    Source: http://us.rd.yahoo.com/dailynews/rss/tech/*http%3A//news.yahoo.com/s/yblog_technews/20120126/tc_yblog_technews/casios-new-smartphone-looks-like-an-oversized-watch-might-survive-the-apocalypse

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    Thursday, January 26, 2012

    Tim Thomas: Six other athletes who snubbed the White House

    Tim Thomas and the Boston Bruins won the NHL's Stanley Cup last June. It's an annual tradition that US championship sports teams receive an invitation from the President to be honored at the White House for their athletic feats.

    However, there is a small portion of those ?privileged? individuals who have turned down such invitations on political, moral and personal grounds. Thomas, the Bruins goalie, is the latest to join the group.

    Here?s a list of six athletes who have snubbed American presidents.

    - Michail Vafeiadis,?Contributor

    The indefinite postponement of the 1986 Chicago Bears White House reception, due to the Space Shuttle Challenger disaster, reached an abrupt end when 25 years later President Obama invited his favorite NFL team.

    However, NFL Hall of Famer Dan Hampton declined the invitation.

    "It's my own personal choice that I choose not to go," Hampton said, according to the Huffington Post.

    ?You know, life's about opportunities and seizing the moment. And you know what, I understand why we didn't go the week after the game -- or two weeks or three weeks -- because if indeed it was the Challenger that the White House and the regular administration was dealing with, I understand that. But there were other months -- March, April, May, June -- we could of went,? he said.

    Source: http://rss.csmonitor.com/~r/feeds/csm/~3/0C7USUZYMX0/Tim-Thomas-Six-other-athletes-who-snubbed-the-White-House

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    Nokia S40: over 1.5 billion served

    Nokia S40: over 1.5 billion servedNokia has announced a major mobile milestone: over 1.5 billion (with a b) Series 40 (S40) handsets sold since the first device -- the 7110 -- was introduced in 1999. "We are incredibly proud to reach this milestone," wrote Nokia's Executive VP of Mobile Phones, Mary McDowell. "It is gratifying to consider how Series 40 devices have made mobile technology accessible." Breeze on past the break for the official PR with more information about the Asha 303 handset knighted number 1,500,000,000, then feel free to weigh in on how long will take the Lumia line to reach the same milestone.

    Continue reading Nokia S40: over 1.5 billion served

    Nokia S40: over 1.5 billion served originally appeared on Engadget on Wed, 25 Jan 2012 13:37:00 EDT. Please see our terms for use of feeds.

    Permalink   |   | Email this | Comments


    Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/4KU8yxGqxCQ/

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    Wednesday, January 25, 2012

    Greek debt hopes shore up markets despite delay

    (AP) ? Hopes that Greece will eventually reach a deal with private creditors on lowering its debt supported markets on Monday, as investors looked past delays in reaching an agreement that would further ease Europe's debt crisis.

    The country's private creditors are being asked to accept longer maturities and lower interest rates on new bonds swapped for their existing ones.

    Greece, which is negotiating alongside fellow eurozone nations and the International Monetary Fund ? its bailout rescuers ? wants interest rates as low as 3 percent on the new bonds. But the private creditors believe that is too low and are aiming for about 4.5 percent.

    Both sides say a deal is nevertheless very close, heartening investors. The euro was the main beneficiary, climbing a further 0.9 percent to $1.2995.

    Greek officials say negotiations on the private debt writedown are continuing over the phone, while no appointment has been set yet for new face-to-face talks this week.

    An agreement is necessary if Greece is to get the next batch of bailout cash that would prevent a devastating debt default ? Greece does not have enough money to cover a euro14.5 billion ($18.7 billion) bond repayment in March. A deal would allow the country to receive a second bailout package from other European governments and the IMF, and cut Greece's debt from an estimated 160 percent of its annual economic output to 120 percent by 2020.

    Greece will likely be the main topic of discussion at a meeting later of the 17 eurozone finance ministers in Brussels.

    "Hopes are high that today's meeting in Brussels will produce some positive plans to tackle the ongoing debt issues and balance out some of the frustration felt by the inability of Greece to come to an agreement with its lenders," said David Jones, chief market strategist at IG Index.

    Those hopes have helped shore up markets at the start of a week, which will also feature the annual meetings in Davos, Switzerland and the U.S. Federal Reserve's first rate-setting meeting of the year.

    In Europe, the FTSE 100 index of leading British shares was up 0.5 percent at 5,759 while Germany's DAX rose 0.2 percent to 6.414. The CAC-40 in France was 0.3 percent higher at 3,332.

    Wall Street was poised for a steady, if unspectacular, opening with little economic news on the calendar ? Dow futures were unchanged at 12,658 while the broader Standard & Poor's 500 futures rose 0.1 percent at 1,310.

    Optimism that Greece will clinch a deal as well as a run of successful European bond auctions and solid economic and corporate news, not least from the U.S. and China, have brightened market sentiment this year. Many stock indexes have risen to five-month highs, while the euro has clambered off 17-month dollar lows to head back towards the $1.30 mark.

    Later in the week, investors will be monitoring the meeting at the Fed.

    Though the Fed is expected to keep its super-loose monetary policy unchanged, there will be great interest in the outcome of the meeting. It will be the first time the Fed will be publishing its interest rate forecasts out to 2016, part of a strategy to enchance communication with financial markets.

    Investors will be particularly interested to see how long it expects interest rates to remain low ? previously the Fed said it expected to keep them low until the middle of 2013.

    "Most, ourselves included, expect the projections to suggest the Fed sees rates on hold well into 2014," said Adam Cole, an analyst at RBC Capital Markets.

    In the oil markets, traders are watching developments in the Persian Gulf, too. Iran has threatened to close the Strait of Hormuz if the U.S. and other countries impose more sanctions on it because of its nuclear program. Many analysts doubt that Iran could set up a blockade for long, but any supply shortages would cause supplies to tighten.

    As a result, prices have remained well-supported ? benchmark crude was up 30 cents at $98.63 a barrel in electronic trading on the New York Mercantile Exchange.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-01-23-World-Markets/id-27209bc98dc04361a09cd8b503485883

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    Tuesday, January 24, 2012

    Paterno's son: JoePa upbeat, fought cancer to end

    This circa 1949 publicity photo released Monday, Jan. 23, 2012 by Brown University shows the late Joe Paterno, as co-captain of the Brown football team in Providence, R.I. Paterno, the former Penn State head football coach, died Sunday, Jan. 22, 2012. He was 85. (AP Photo/Brown University)

    This circa 1949 publicity photo released Monday, Jan. 23, 2012 by Brown University shows the late Joe Paterno, as co-captain of the Brown football team in Providence, R.I. Paterno, the former Penn State head football coach, died Sunday, Jan. 22, 2012. He was 85. (AP Photo/Brown University)

    A mural is shown on the side of a student bookstore, with a likeness of legendary Penn State football coach Joe Paterno on it wearing a halo that was added Monday, Jan 23, 2012, in State College, Pa.. Paterno, a sainted figure at Penn State for almost half a century but scarred forever by the scandal involving his one-time heir apparent, died Sunday, Jan. 22, 2012 in State College. He was 85. (AP Photo/Gene J. Puskar)

    People stop by a statue of former Penn State football coach Joe Paterno to pay their respects on Monday, Jan. 23, 2012 in State College, Pa. Paterno died Sunday at age 85, less than three months after being diagnosed with lung cancer. (AP Photo/Gene J. Puskar)

    (AP) ? Joe Paterno was upbeat and confident in his final days and didn't die broken-hearted over his firing in November as Penn State's longtime football coach, his son said Monday.

    Scott Paterno said his Dad was "serenely calm," before his death from lung cancer on Sunday, antsy to leave the hospital so he could start planning a vacation with his wife, Sue.

    Paterno was abruptly dismissed after 46 years amid a child sex abuse scandal involving a former assistant coach.

    During a telephone interview with The Associated Press, Scott Paterno said his father's health had deteriorated by Friday afternoon, prompting the family to announce Saturday that the 85-year-old Paterno was in serious condition. He died the following morning.

    "He wanted his family in his room. He wanted to be around people. He wanted to talk," the son said. "He wanted to have people, even when he had trouble speaking, he wanted people around him talking. How are your kids? It was so natural. It was like we were having dinner around the kitchen table. It just happened to be his hospital bed."

    And, he said: "Even at the end when it was clear that he passed a line of no return, it was never a moment of bitterness. It was never a moment of fear. He was serenely calm, even right up to the end."

    The Paternos would have been married six decades this year. Along with their five children, Sue Paterno was at her husband's bedside at Mount Nittany Medical Center when he died.

    "If there's any message I think my father would pass on to everybody at this point, it's 'let's build this thing up.' He was so positive and so confident at the end of his life that the things that were important about this place would endure.

    "And that's why he was at peace," Scott Paterno said, before joking, "That, and (that) my mother was willing to put up with him all these years."

    The Paternos' plans for a long promised six-week honeymoon trip were snatched away by the disease that took his life.

    The actual honeymoon? A three-day trip to Virginia Beach ? with a stop to see a recruit on the way down.

    Paterno re-entered the hospital on Jan. 13, with his family fully expecting him to return home despite his increased frailty.

    They thought it was simply a matter of getting him stabilized.

    As recently as last Wednesday, Paterno was counting on his fingers the number of days he had been in the hospital, hoping to get out.

    "One, two, three, four, five. I've been here five days. I'm coming home," his son quoted his Dad as saying.

    Though the old coach was on a respirator that made it difficult to talk, it didn't stop him from teasing Scott on Thursday about his weight. Again. Dad playfully pointed to his son's belly.

    "He did that every time," Scott Paterno said.

    There were no balloons or flowers in Paterno's room. His son suspects his mother sent them to other patients in the hospital.

    But there was a Penn State sweat shirt in there.

    "His life is Penn State through and through," Scott Paterno said, speaking of his father in the present tense. "He understood that and it never once occurred to him to be bitter toward Penn State."

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-24-Paterno-Final%20Days/id-898487e270b74969957ed6b3b87efad4

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    Monday, January 23, 2012

    State of Union: Obama to take on economic anxiety (AP)

    WASHINGTON ? Eager to command center stage in a year dominated by Republican infighting, President Barack Obama is polishing a State of the Union address that will go to the heart of Americans' economic anxiety and try to sway voters to give him four more years. He will speak Tuesday to a nation worried about daily struggles and unhappy with his handling of the economy.

    Obama's 9 p.m. EST address before a politically divided Congress will be built around ideas meant to appeal to a squeezed middle class. He is expected to urge higher taxes on the wealthy, propose ways to make college more affordable, offer new steps to tackle a debilitating housing crisis and try to help U.S. manufacturers expand hiring.

    Designed as a way for a president to update the nation and recommend ideas to Congress, the State of the Union address has become more than that, especially during that one window when the address falls during the re-election year of an incumbent. It is televised theater ? and Obama's biggest, best chance so far to offer a vision for a second term.

    He will frame the campaign to come as a fight for fairness for those who are struggling to keep a job, a home or college savings and losing faith in how the county works.

    The speech will be principally about the economy, featuring the themes of manufacturing, clean energy, education and American values.

    No matter whom Obama faces in November, the election is likely to be driven by the economy, and determined by which candidate wins voters' trust on how to fix it. More people than not disapprove of Obama's handling of the economy.

    The overarching political goal is to give voters a contrast between his vision of a government that tries to level the playing field and those office-seekers who, in his view, would leave people on their own. Without naming them, Obama has in his sights those after his job, including Republicans Mitt Romney and Newt Gingrich.

    The presidential campaign sets an unmistakable context for the speech, right down to the nation's income gap between haves and have-nots. Obama will speak on a few hours after Romney, a former governor and businessman whose wealth is the hundreds of millions of dollars, will release tax records for 2010 and 2011.

    The lines of argument between Obama and his rivals are already stark, with America's economic insecurity and the role of government at the center.

    The president has offered signals about his speech, telling campaign supporters he wants an economy "that works for everyone, not just a wealthy few." Gingrich, on the other hand, calls Obama "the most effective food stamp president in history." Romney says Obama "wants to turn America into a European-style entitlement society."

    Obama's tone will be highly scrutinized given that his address falls smack in the middle of a fierce and frenzied Republican presidential nomination process. He will make bipartisan overtures to lawmakers but will leave little doubt he will act without opponents when it's necessary and possible, an approach his aides say has let him stay on offense.

    The public is more concerned about domestic troubles over foreign policy than at other any time in the past 15 years, according to a new survey by the Pew Research Center. Some 81 percent want Obama to focus his speech on domestic affairs, not foreign ones; just five years ago, the view was evenly split.

    On the day before Obama's speech, his campaign released a short Web ad showing monthly job losses during the end of the Bush administration and the beginning of the Obama administration, with positive job growth for nearly two Obama years. Republicans assail him as failing to achieve a lot more.

    House Speaker John Boehner, responding to reports of Obama's speech themes, said it was a rehash of unhelpful policies. "It's pathetic," he said.

    Obama will offer economic proposals for this year, despite long odds against getting the help he would need from Republicans.

    Presidential spokesman Jay Carney said Monday that Obama is not conceding the next 10 months to "campaigning alone" when people need economic help. On the goals of helping people get a fair shot, Carney said: "There's ample room within those boundaries for bipartisan cooperation and for getting this done."

    For three days following his speech, Obama will promote his ideas in five states key to his re-election bid: Iowa, Arizona, Nevada, Colorado and Michigan. He speaks on Friday about college affordability at the University of Michigan.

    Meanwhile, the Republican race is suddenly a race again, given Gingrich's resounding win in the South Carolina primary over the weekend. Romney, who appeared the strong front-runner coming into that primary, is now focusing on Gingrich more than Obama as the GOP contest unfolds in Florida.

    Vice President Joe Biden, in an interview with radio host Ryan Seacrest, said Monday there is no ideological difference between any of the Republicans seeking to challenge Obama. He said the campaign will offer the clearest choice in which direction to take the country since the era of the Great Depression.

    Polling shows Americans are divided about Obama's overall job approval but unsatisfied with his handling of the economy.

    Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120124/ap_on_go_pr_wh/us_state_of_the_union

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    SC-2012 Primary: 37% Gingrich, 28% Romney, 16% Santorum, 14% Paul (PPP 1/18-20)

    Public Policy Polling (D)
    1/18-20/12; 1,540 likely Republican primary voters, 2.5% margin of error
    Mode: Automated phone
    PPP release

    South Carolina

    2012 President: Republican Primary
    37% Gingrich
    28% Romney
    16% Santorum
    14% Paul
    (chart)

    "; var coords = [-5, -72]; // display fb-bubble FloatingPrompt.embed(this, html, undefined, 'top', {fp_intersects:1, timeout_remove:2000,ignore_arrow: true, width:236, add_xy:coords, class_name: 'clear-overlay'}); });

    Source: http://www.huffingtonpost.com/2012/01/20/sc-2012-primary-37-gingri_n_1220410.html

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    Sunday, January 22, 2012

    GOP leaders slow to embrace Romney ? or his rivals (AP)

    WASHINGTON ? Mitt Romney may be the front-runner for the GOP nomination for president, but he has yet to win over most of the national party leaders whose help he will need to defeat President Barack Obama in November.

    The upside for Romney: They aren't supporting anyone else either.

    The Associated Press has polled 87 members of the Republican National Committee who are to attend the party's national convention this summer as free agent delegates, able to support any candidate for president they choose, regardless of what happens in the primaries.

    The results: Romney got support from 14, far more than anyone else but hardly a stampede of endorsements. Former House Speaker Newt Gingrich and Texas Gov. Rick Perry got two each, while Texas Rep. Ron Paul and former Pennsylvania Sen. Rick Santorum each got one. The poll was completed before Perry dropped out of the race Thursday.

    Sixty-seven of the RNC members contacted by the AP said they were undecided or simply waiting to see how the race plays out before making a public endorsement.

    "If I thought there was someone who stood head and shoulders above everyone else, I would have endorsed," said Jeff Johnson, an RNC member and county commissioner from Minnesota. "I see pluses in all of them, but I decided not to come out in favor of anybody."

    Pennsylvania GOP Chairman Robert Gleason said he saw no reason to endorse anyone because a competitive primary is good for the party and the eventual nominee by vetting the candidate while generating publicity and excitement about the race.

    "It's working out great for us, and one of these people that is competing with (Romney) could end up being vice president," Gleason said. "I'm pleased with the way things are developing. We're getting all the publicity. It's been pretty favorable for us."

    Romney appeared to finish slightly ahead of Santorum in the hours after the Iowa caucuses Jan. 3. However, the Iowa GOP certified vote totals Thursday showing Santorum ahead of Romney. The party decided not to declare a winner because of problems with a few precinct reports.

    Romney won handily in New Hampshire last week, and he leads his Republican rivals in the polls nationally and in South Carolina, which votes Saturday. Still, the former Massachusetts governor has been unable to solidify support from many Republicans, some of whom question his conservative credentials.

    Stephen Scheffler, an RNC member from Iowa, said he would support Romney if he were the nominee, but he's not excited about the prospect, despite Romney's finish in Iowa.

    "He doesn't want to talk to certain segments of the Republican Party," Scheffler said of Romney. "If he's the nominee and they open all these victory offices across Iowa, it's going to be pretty challenging to find volunteers."

    Each state plus the District of Columbia and five U.S. territories gets three members on the Republican National Committee. All of them are automatically invited to attend the party's national convention in Tampa, Fla., in August, with a few exceptions. The RNC members from New Hampshire, South Carolina, Florida, Michigan and Arizona have been excluded ? for now ? as part of the penalties they received for holding primaries earlier than party rules allowed.

    In many states, RNC members must support the winner of primaries or caucuses in their states. The AP identified 37 states and territories in which the RNC members will be free to support any candidate they choose.

    AP reporters started contacting the 111 RNC delegates from these states after Romney won the New Hampshire primary. They were able to reach nearly 80 percent of them.

    The RNC delegates make up less than 5 percent of the 2,286 delegates slated to attend the GOP convention, giving them little power to determine the nominee. But these party leaders will be expected to provide manpower, money, local connections and expertise this fall, when the GOP nominee will rely on the party faithful to help defeat Obama.

    It will take 1,144 delegates to win the GOP nomination. Romney now has 33 delegates, including those won in primaries and caucuses as well as endorsements from RNC members. Santorum is next with 13.

    Joseph Trillo, a state lawmaker and RNC member from Rhode Island, said his support for Romney comes down to political pragmatism.

    "He's the only one who I know can beat Obama," Trillo said.

    Herbert Schoenbohm, the GOP chairman in the Virgin Islands, said that beating Obama is important, but his support for Romney goes much deeper.

    "I'm for (Romney) because he has the best leadership skills," Schoenbohm said in a phone interview. "He made it work in Massachusetts, and that was hard to do in a Democratic state."

    Lawrence Kadish, an RNC member from Long Island, N.Y., challenged that assessment, saying Gingrich "towers head and shoulders over those other candidates. I don't view Mr. Romney as having a deep rudder, but he's OK."

    ___

    Lauren Johnert, Associated Press deputy manager for election research and quality control, contributed to this report, along with AP writers Pat Condon in St. Paul, Minn., Marc Levy in Harrisburg, Pa., Mike Glover in Des Moines, Iowa, David Klepper in Providence, R.I., and George M. Walsh in Albany, N.Y.

    Source: http://us.rd.yahoo.com/dailynews/rss/obama/*http%3A//news.yahoo.com/s/ap/20120120/ap_on_el_pr/us_gop_superdelegates

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    Indians' Carmona arrested for false identity

    FILE - In this Aug. 22, 2011, file photo, Cleveland Indians' Fausto Carmona pitches against the Seattle Mariners in a baseball game in Cleveland. A spokesman for police in the Dominican Republic says the Indians pitcher has been arrested for using a false identity. Maximo Baez Aybar said Thursday, Jan. 19, 2012, that Carmona was arrested outside the U.S. consulate in Santo Domingo. Carmona had gone there to renew his visa so he could return to the United States. Baez said Carmona's real name is apparently Roberto Hernandez Heredia and his age is 31, three years older than the pitcher claimed. The name of his lawyer was not yet known. (AP Photo/Mark Duncan, File)

    FILE - In this Aug. 22, 2011, file photo, Cleveland Indians' Fausto Carmona pitches against the Seattle Mariners in a baseball game in Cleveland. A spokesman for police in the Dominican Republic says the Indians pitcher has been arrested for using a false identity. Maximo Baez Aybar said Thursday, Jan. 19, 2012, that Carmona was arrested outside the U.S. consulate in Santo Domingo. Carmona had gone there to renew his visa so he could return to the United States. Baez said Carmona's real name is apparently Roberto Hernandez Heredia and his age is 31, three years older than the pitcher claimed. The name of his lawyer was not yet known. (AP Photo/Mark Duncan, File)

    El pitcher dominicano de los Indios de Cleveland, Fausto Carmona, gesticula en un partido contra los Rangers de Texas el 15 de septiembre de 2011. Carmona fue arrestado en Santo Domingo el 19 de febrero de 2012 por utilizar una identidad falsa. (AP Photo/Tony Gutierrez, File)

    (AP) ? From year to year and game to game, the Cleveland Indians never knew what to expect from Fausto Carmona.

    On Thursday, he stunned them again.

    Carmona, the Indians' opening-day starter last season, was arrested in the Dominican Republic for allegedly using a false identity. Officials in his native country are contesting his real name and birthdate.

    Police spokesman Maximo Baez Aybar said Carmona was arrested in Santo Domingo outside the U.S. consulate, where he had gone to renew his visa. Carmona had played winter ball in the Dominican as he prepared to report to the Indians' training camp in Goodyear, Ariz., next month.

    At this point, his future with the club is uncertain.

    Aybar said Carmona's real name is apparently Roberto Hernandez Heredia and he's 31, three years older than the pitcher claimed. The Indians list Carmona's birthday as Dec. 7, 1983, in their 2011 media guide.

    "We were recently made aware of the situation that occurred today in the Dominican Republic and are currently in the process of gathering information," Indians general manager Chris Antonetti said. "We are not prepared to make any additional comment at this time."

    Carmona's agent said he was caught off-guard by the arrest and that there are Dominican lawyers working on the player's behalf. He did not disclose the names of the lawyers.

    "This took us by complete surprise," agent Jay Alou said. "What we have to do now is wait to find out the process that has to be done with the consulate with this new identity in order to see if he can get a new work visa."

    Carmona's arrest is the second involving a major leaguer in four months in a false identity case. Miami Marlins reliever Leo Nunez was arrested in September. Last month, an apologetic Nunez said he falsified his identify when he was young so he could play professional baseball. Nunez's real name is Juan Carlos Oviedo and he's 29, a year older than listed in the Marlins' media guide.

    Carmona's career in Cleveland has been one of extremes.

    After going 1-10 in 2006, the right-hander with a wicked slider came out of nowhere to win 19 games in 2007, shocking the Indians who had briefly experimented with him as a closer. Carmona, though, followed up with a disappointing 2008 season, and in 2009 the club sent him to the lower minors to work on his mechanics.

    Carmona rebounded to win 13 games in 2010 in manager Manny Acta's first season. Although he went just 7-15 last season, Carmona stayed healthy, didn't miss a start and was expected to be part of the starting rotation this season. The Indians picked up his $7 million option for 2012 in October.

    The Indians signed Carmona to a four-year contract in 2008. The club has options on him for 2013 at $9 million and 2014 at $12 million.

    Cleveland signed Carmona as a free agent in 2000.

    ___(equals)

    Soldevila reported from the Dominican Republic.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-19-Indians-Carmona%20Arrested/id-795eb2b47d4d4d2aa24b474da9e68042

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    Saturday, January 21, 2012

    Raspberry Pi demos Model B computer's AirPlay capabilities (video)

    Just a few days after announcing that production of its Model B Linux computer is underway, Raspberry Pi has now unveiled a preview of what its single board device can do when combined with AirPlay. In a video published this week, a Raspberry Pi developer demonstrated how to stream content from an iPad to the ARM-based Model B, using only an HDMI-equipped TV and an AirPlay app. It's as seamless as dancing cows are beautiful. Still no word yet on when this $35 will begin shipping, but in the meantime, be sure to check out the demo video, after the break.

    Continue reading Raspberry Pi demos Model B computer's AirPlay capabilities (video)

    Raspberry Pi demos Model B computer's AirPlay capabilities (video) originally appeared on Engadget on Fri, 20 Jan 2012 06:40:00 EDT. Please see our terms for use of feeds.

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    Source: http://www.engadget.com/2012/01/20/raspberry-pi-demos-model-b-computers-airplay-capabilities-vide/

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