Friday, May 31, 2013

Patrick Stewart hugs domestic-abuse survivor

Celebs

8 hours ago

IMAGE: Patrick Stewart

Reuters file

Patrick Stewart told the Comicpalooza audience that his mother was blamed for the abuse rained on her by his father.

On television, he was the almost unflappable Captain Jean-Luc Picard on "Star Trek: The Next Generation." But Patrick Stewart was raised in a poor household with an abusive father, and the experience gave him the fire to work for such causes once he had the fame to make himself heard.

Stewart appeared at Comicpalooza in Texas over the Memorial Day weekend, and while there, answered questions from audience members.

Heather Skye, who blogs at Lemon Sweetie, thanked Stewart for a speech he gave at an Amnesty International event about domestic violence, saying that she had come through a similar event and appreciated his speaking out, and asked him about what non-acting work he's the most proud of.

And then things got personal. Stewart, who has spoken about his father's abuse before, referenced his own childhood in 1940s England. "The work that I do in campaigns about violence towards women, particularly domestic violence, grew out of my own childhood experience," he said.

He discussed the specific groups he works with, and went on to say, "I do what I do in my mother's name, because I couldn't help her then. Now I can."

Stewart said his father, a World War II veteran, was then said to suffer from severe shellshock, but would today be diagnosed with post-traumatic stress disorder. He works with both the veterans' mental-health charity Combat Stress as well as the domestic-violence shelter Refuge, saying he does so because of both of his parents.

"As a child, I heard in my home doctors and ambulance men say, 'Mrs. Stewart, you must have done something to provoke him,'" Stewart said to Skye and the crowd. "'Mrs. Stewart, it takes two to make an argument.' Wrong! WRONG! My mother did nothing to provoke that, and even if she had, violence is never ever a choice that a man should make. Ever!"

The crowd gave Stewart a standing ovation, and shortly after, he walked into the crowd and hugged Skye. She wrote on her blog, "He told me 'You never have to go through that again, you?re safe now.' I couldn?t stop thanking him. His embrace was so warm and genuine. It was two people, two strangers, supporting and giving love. And when we pulled away he looked (straight) in my eyes, like he was promising that. He told me to take care. And I will."

Source: http://www.today.com/entertainment/patrick-stewart-hugs-domestic-abuse-survivor-tells-violence-his-childhood-6C10145579

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EU agency calls for curbs on GSK, Valeant epilepsy drug

LONDON (Reuters) - Use of an epilepsy drug developed by GlaxoSmithKline and Valeant Pharmaceuticals should be restricted to patients for whom other anti-epileptic medicines have proved inadequate or not tolerated, EU regulators said on Friday.

The European Medicines Agency said the move followed cases of abnormal coloring of the skin, nails, lips and eye tissues, including the retina, in some patients who took Trobalt.

It recommended a comprehensive eye examination should be performed at the start of treatment and at least every six months during treatment. Among 55 patients receiving Trobalt in long-term studies examined so far, 15 had retinal pigmentation, the agency added.

Abnormal coloring of the retina can result in impaired vision.

The Food and Drug Administration issued a similar warning about the drug - which is sold in the United States as Potiga - last month.

(Reporting by Ben Hirschler)

Source: http://news.yahoo.com/eu-agency-calls-curbs-gsk-valeant-epilepsy-drug-094702727.html

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Source: http://www.thehollywoodgossip.com/2013/05/prancercise-finally-catching-on/

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Jared Leto: I was 'food-stamp poor'

Celebs

23 minutes ago

IMAGE: Jared Leto

Getty Images

Jared Leto in 2013.

He's a movie star and a rock musician today, but in his childhood, Jared Leto was "food-stamp poor," he tells style catalog and publication Mr. Porter.

Leto and his brother Shannon were raised by a single mom who moved often, but infused her sons with a sense of creativity and the arts.

"It was the 1970s, the age of the artist and the hippy, and my exposure to that shaped me in a really deep way," he said. "I had no concept of the word 'fame'; or a notion of success or money. We grew up very poor, so our world wasn't anywhere near that kind of stuff. You have to do what is important to you and protect that."

Leto is known to many as Angela Chase's crush Jordan Catalano in the 1994-1995 cult TV favorite "My So-Called Life." He's also starred in such films as "American Psycho," "Requiem for a Dream," and "Urban Legend," but his second love is music. Leto and his brother perform together as part of the rock group 30 Seconds to Mars.

The band's latest album, "Love Lust Faith and Dreams," features a song that harks back to Leto's childhood, as "Depuis Le D?but," the final song on the album, closes by featuring a music box playing the theme from "Swan Lake."

"My mother used to put my little brother and me to sleep by playing that exact music box," he said. "And we wanted to put a little bit of our life on there. The whole record is very personal and I hope it is an album that can be transformative."

Source: http://www.today.com/entertainment/jared-leto-i-was-food-stamp-poor-6C10136195

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Thursday, May 30, 2013

Ted Cruz?s thoughtful approach to immigration reform (Powerlineblog)

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Study: Doctors often on board to help sick fliers

Is there a doctor on board? Surprisingly often, there is ? in half of in-flight medical emergencies ? and sick airline passengers almost always survive, a new study finds.

The research is the largest look yet at what happens to people who develop a medical problem on a commercial flight ? about 44,000 of the 2.75 billion passengers worldwide each year, researchers estimate.

Most cases don't require diverting a plane as the study's leader, Dr. Christian Martin-Gill, advised a pilot to do two years. He works for MD-STAT, a service at the University of Pittsburgh Medical Center that advises about 20 major airlines on how to handle in-flight emergencies. Another large service is based in Phoenix.

Martin-Gill handled a call when a passenger seemed to be having a heart attack on a flight from Europe to the U.S. The man's implanted defibrillator had shocked his heart five times to try to restore normal rhythm.

"The aircraft was in the middle of its destination, flying over the Atlantic," so he recommended landing at Newfoundland off the Canadian coast to get the man to the nearest hospital, Martin-Gill said.

The federally funded study reviewed about 12,000 cases handled by the Pittsburgh center over nearly three years. Results are in Thursday's New England Journal of Medicine. Researchers found:

?The odds of a medical emergency are 1 per 604 flights, or 16 per 1 million passengers.

?Planes had to be diverted for emergency help in only 7 percent of cases.

?Doctors were on board and volunteered to help in 48 percent of cases; nurses and other health workers were available in another 28 percent. Only one-third of cases had to be handled by flight attendants alone.

?The most common problems: Dizziness or passing out (37 percent of cases); trouble breathing (12 percent) and nausea or vomiting (10 percent).

?About one-fourth of passengers were evaluated at a hospital after landing and 9 percent were admitted, usually with stroke, respiratory or cardiac symptoms.

?Out of nearly 12,000 cases, a defibrillator was applied 137 times, including in 24 cases of cardiac arrest, where the heart had stopped. (Sometimes defibrillators are used to analyze an irregular heart rhythm to help doctors figure out what to do, not necessarily to deliver a shock.)

?Of the cases in this study, only 36 deaths occurred, 30 of them during the flight and the others after landing.

?Pregnancy-related problems were generally rare ? 61 cases, in this study ? and two-thirds of them involved women less than 24 weeks along with possible miscarriages. Air travel is considered safe up to the 36th week, or the last month, of pregnancy. Only three cases of women in labor beyond 24 weeks of pregnancy led to a plane being diverted.

Dr. Lisa Rosenbaum, a University of Pennsylvania cardiologist, helped in a case like that in 2007, on a flight from Boston to Portland, Ore. The passenger was three months from her due date but was having contractions every minute ? something that can often be stopped with drugs and treatment at a hospital but not in midair.

"It was clear to me that labor was imminent and that we needed to land the plane," so, on her advice, the pilot diverted to upstate New York, Rosenbaum said. "It was one of the scariest experiences of my life. It's not like taking care of a patient in the hospital."

Dr. David Rogers, a pediatric surgeon at the University of Alabama at Birmingham School of Medicine, felt that fear five years ago when an elderly woman had trouble breathing during a flight to Atlanta from Toledo, Ohio.

Being a specialist at treating children rather than adults, "my first reaction was to look around and hope there would be somebody else" more qualified to help, he said.

Luckily, a flight attendant had already given the woman an oxygen mask and she seemed to be improving, so he felt the plane could continue to Atlanta, the woman's home. Trying to determine whether to divert a plane was a tough call, he said.

"I'm making a decision that's going to affect a plane full of people," not just the patient, Rogers said.

Some passengers may fear liability if they help in such situations, but a Good Samaritan law protects those who do so, the study notes. And although health workers are not legally obliged to help, they have a moral obligation to do so, the authors write.

And you never know what kind of help will be requested. Martin-Gill said a partner once was consulted when a dog suffered a cardiac arrest during a flight. He didn't know how things turned out.

___

Online:

Journal: http://www.nejm.org

___

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

Source: http://news.yahoo.com/study-doctors-often-board-help-sick-fliers-213528634.html

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Wednesday, May 29, 2013

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SEO Techniques And Methods All Websites Should Utilize ...

Most businesses today have an online presence that helps them increase their reputation or sales. It is important that these businesses take their ranking seriously and use search engine optimization to improve their site and to advance it on the search engines. This article has tips on the best strategies and improvements that need to be made.

When setting up your site for SEO, keep an eye on keyword density. You want to have your major keywords at about 3 to 7 percent of the total text. Anything higher than about 10 percent starts to look suspicious to the search engine, as if you are using keyword stuffing to boost page rank.

One easy search engine optimization technique you can implement is to include keywords in your HTML title tag. This helps the search engines to easily determine what your page is about. Not only that, but when visitors search for your keyword, it will show up in bold in the search results, drawing more attention to your listing.

Backlinks

Backlinks

When setting up your site using SEO, don?t forget the importance of the site-map. Search engines spiders love site-maps, as do human users. It shows both groups where everything is on your site, and increases the keyword density of your pages. Site-maps also help boost your linkage ratings similarly to backlinks.

Keywords are the backbone of search engine optimization. Keywords, when written, should be italicized, underlined, and bold when possible. Check into the backlinks of those you consider competitors. Copy their backlinks creatively. You need backlinks pointing at your site as much as possible. Get backlinks from sites that have the same theme as yours.

Writing and posting reviews for your product are a great way to increase your traffic. By creating a review of the product, targeting the product keywords and getting backlinks to the review to enhance its search rating, you can create a mindset for buying and direct those viewers appropriately.

Writing and posting reviews for your product are a great way to increase your traffic. By creating a review of the product, targeting the product keywords and getting backlinks to the review to enhance its search rating, you can create a mindset for buying and direct those viewers appropriately.

Link Building

When it comes to search engine optimization, you must remember that content is always king. The key to attracting visitors to your page is to load up on as much unique, relevant and well-written content as you can about your particular keyword. Link building only works if you have good content to back it up and keep readers coming back for more.

You need to treat link building as a process that keeps going. Spend a few minutes every day on your link campaign. You can pay for services that will build your links for you, though those have proven not to be as effective as taking the time and doing it yourself.

Start a blog and do your best to stay in touch with other blog owners that are in the same industry. if you read a lot of different blogs and leave comments on them you will start to build relationships and possibly help increase your exposure and help you with your link building.

Start a blog and do your best to stay in touch with other blog owners that are in the same industry. if you read a lot of different blogs and leave comments on them you will start to build relationships and possibly help increase your exposure and help you with your link building.

Start a blog and do your best to stay in touch with other blog owners that are in the same industry. if you read a lot of different blogs and leave comments on them you will start to build relationships and possibly help increase your exposure and help you with your link building.

With search engine optimization, your blog or website can get way more traffic by appearing early on lists of search results for terms related to your business. Apply these easy, free, and effective techniques to maximize your traffic and use that traffic to maximize your profits. Why wait? Start now!


Source: http://www.advsecret.com/seo-techniques-and-methods-all-websites-should-utilize/

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NASCAR waits on Fox review for camera decision ? Artesia News

In this photo provided by Fernando Echeverria, security personnel assist a fan injured by a broken television camera cable during the NASCAR Sprint Cup series Coca-Cola 600 auto race at Charlotte Motor Speedway in Concord, N.C., Sunday, May 26, 2013. (AP Photo/Fernando Echeverria)

In this photo provided by Fernando Echeverria, security personnel assist a fan injured by a broken television camera cable during the NASCAR Sprint Cup series Coca-Cola 600 auto race at Charlotte Motor Speedway in Concord, N.C., Sunday, May 26, 2013. (AP Photo/Fernando Echeverria)

CONCORD, N.C. (AP) ? Fox Sports said on Monday it still had not determined why an overhead TV camera cable snapped during the Coca-Cola 600.

The network says a full investigation is under way and use of the camera is suspended indefinitely. Earlier, NASCAR said it would wait for Fox Sports to conclude its review before deciding if such technology would be used in the future.

Charlotte Motor Speedway said 10 people were injured when part of the drive rope landed in the grandstand; three were taken to hospitals. All were checked out and released soon after.

In a statement, Fox said it was ?relieved and thankful to know that the injuries to fans caused then CAMCAT malfunctioned at Charlotte Motor Speedway were minor.?

The network again apologized for the disruption.

Several drivers, including then-leader Kyle Busch, reported damage to their cars from the rope.

NASCAR spokesman Kerry Tharp told The Associated Press on Monday that there were no plans to use the system at upcoming races ?so we?ll have ample time to review.?

The network said the system was provided by Austrian company CAMCAT. The rope that failed was certified for a breaking strength of 9,300 pounds and was only bearing less than 900 pounds of force during the race, according to Fox Sports.

The network said it?s reviewing with CAMCAT equipment maintenance records, history and installation information and plans to share its findings with NASCAR and Charlotte Motor Speedway.

The network said the system was used successfully at the Daytona 500 and was set up and working at last week?s Sprint All-Star race in Charlotte. Fox?s final NASCAR telecast this year comes Sunday at Dover International Speedway.

Tharp said NASCAR would let the network determine what went wrong.

?We?ll sync up with them on what they have learned this week and go from there,? he said.

The network explained how the drive rope moves the camera back and forth and failed near its turn one connection. The camera, it said in a statement, did not come down ?because the guide ropes acted as designed.?

The rope, Fox said, was made of Dyneema, which it described as ?an ultra-strong synthetic that has the same approximate strength of a steel wire with the same diameter.? It said the rope was less than a year old, had been factory-tested by its manufacturer and its breaking strength was certified before shipment. The rope was also inspected by CAMCAT when it was received last June.

According to OnlineRopes.com, Dyneema has the ?highest strength-to-weight ratio of any manmade material in the world. On weight-to-weight base, it is up to 15 times stronger than steel.?

The pictures such cameras provide can be extraordinary. But in this case, the failure brought confusion and chaos to the racers and the fans.

Coca-Cola 600 winner Kevin Harvick thought he was imagining things when he noticed the black rope on the track. He was among the lucky ones who escaped without damage. Busch said he heard a ?thunk? when he ran over it and knew he?d have problems.

Busch used a cellphone to take a picture of the mangled metal around his front, right-side wheel so his team could figure out how to repair the damage.

Marcos Ambrose dragged a piece of the rope that got caught up in his car behind him on the track. Mark Martin also reported problems after driving over the rope.

NASCAR red-flagged the race for about 30 minutes and allowed teams back to their pits to get their cars back to race trim.

NASCAR first threw a caution flag before two red flags came out. It eventually allowed the cars to come into the pits, giving crews 15 minutes to work on their cars.

During the break, Busch?s crew frantically worked to repair several problems to the right front wheel well. After completing repairs, the crew slapped high-fives as the car rolled back on the track.

Busch remained competitive and was running in the top five at the midpoint of the race. But his night ended in frustration when his engine blew up on lap 253. He said the engine problem was not related the rope damage. He thanked NASCAR for how it handled the unique stoppage.

?I commend NASCAR for taking the initiative and letting us repair our damaged cars from the issue we had,? Busch said.

Busch said he never saw the nylon rope.

Ambrose wound up 10th behind Harvick, the second top-10 finish of the year for the Richard Petty Motorsports team.

Kasey Kahne led 156 laps, most of the night, and was second to Harvick. He was as bewildered as everyone else with the TV cable across the track.

?I?ve never seen anything like it,? he said. ?I came around turn four, saw it wrapped around Kyle?s car, hit mine. I thought I was seeing things.?

The camera hung in place over the large painted logo on the grass between the start-finish line and pit road.

Fox broadcaster Chris Myers apologized during the telecast several times to fans, drivers and race teams for the disruption. The network?s statement offered ?a sincere ?thank you? to the staff at CMS for attending to the injuries and keep us informed on this developing situation.?

Busch wasn?t sure anybody had seen that happen before and offered a solution: ?Maybe now we can be rid of that thing.?

This entry was posted on May 27, 2013, 5:30 pm and is filed under Sports. You can follow any responses to this entry through RSS 2.0. Both comments and pings are currently closed.

Source: http://www.artesianews.com/2013/05/27/ap-news/sports-ap-news/nascar-waits-on-fox-review-for-camera-decision/

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Consoler in chief: President Obama?s post-tragedy speeches, from Tucson to Moore

President Obama tours the devastation in Moore, Okla., May 26, 2013. (Mandel Ngan /AFP/Getty Images)

"I'm just a messenger here today, letting everybody here know that you are not alone, that you've got folks behind you."

After touring the tornado damage in Oklahoma, on Sunday, President Barack Obama found himself in an all-too-familiar role: consoler in chief. From Tucson to Newtown, Joplin to Moore, Obama's visits to cities and towns torn apart by tragedy have become an important, if sadly routine, part of his presidency.

"Whenever I come to an area that's been devastated by some natural disaster like this, I want to make sure everybody understands I'm speaking on behalf of the entire country," Obama said, standing where the Plaza Towers Elementary School once stood. "Everywhere, fellow Americans are praying with you."

"This is a strong community with strong character," he continued. "There's no doubt they're going to bounce back."

A little over a month ago at a church in Boston's South End, the president delivered a similar message in the wake of the marathon bombings.

"Scripture tells us to run with endurance the race that is set before us," Obama said at the interfaith service. "This doesn't stop us. And that's what you've taught us, Boston. That's what you've reminded us, to push on. To persevere. To not grow weary. To not get faint. Even when it hurts. Even when our heart aches. We summon the strength that maybe we didn't even know we had, and we carry on. We finish the race."

In December in Newtown, Conn., following what Obama later said was the toughest day of his presidency, the consoler in chief spoke to a community which had just lost 20 children in the massacre at Sandy Hook Elementary School.

"I come to offer the love and prayers of a nation," Obama said at the interfaith service. "I am very mindful that mere words cannot match the depths of your sorrow, nor can they heal your wounded hearts. I can only hope it helps for you to know that you're not alone in your grief, that our world, too, has been torn apart, that all across this land of ours, we have wept with you. We've pulled our children tight. And you must know that whatever measure of comfort we can provide, we will provide. Whatever portion of sadness that we can share with you to ease this heavy load, we will gladly bear it. Newtown, you are not alone."

Obama began his speech in Newtown by quoting scripture: "Do not lose heart. Though outwardly we are wasting away, inwardly, we are being renewed day by day."

He did the same in Aurora, Colo., last July, after visiting a victim of the deadly movie theater shootings:

Scripture says that "He will wipe away every tear from their eyes, and death shall be no more. Neither shall there be mourning, nor crying, nor pain anymore, for the former things have passed away." And when you have an opportunity to visit with families who have lost their loved ones?as I described to them, I come to them not so much as president as I do as a father and as a husband. And I think that the reason stories like this have such an impact on us is because we can all understand what it would be to have somebody that we love taken from us in this fashion?what it would be like and how it would impact us.

In Tuscon, Ariz., in 2011, the president addressed the community at an interfaith service days after a gunman killed 6 people and wounded 13 in an attempted assassination of Rep. Gabrielle Giffords.

"I have come here tonight as an American who, like all Americans, kneels to pray with you today and will stand by you tomorrow," Obama said. "There is nothing I can say that will fill the sudden hole torn in your hearts. But know this: The hopes of a nation are here tonight. We mourn with you for the fallen. We join you in your grief."

He quoted scripture there, too:

There is a river whose streams make glad the city of God,
the holy place where the Most High dwells.
God is within her, she will not fall;
God will help her at break of day.

In Moore on Sunday, President Obama did not select a passage from the Bible himself, instead relaying an anecdote from media coverage of the tornado.

"There was a story that really struck me," Obama said. "In the rubble was found a Bible, open to the words that read: A man will be as a hiding place from the wind, and a cover from the tempest.' And it's a reminder, as scripture often is, that God has a plan, and it's important, though, that we also recognize we're an instrument of his will. And we need to know that as fellow Americans, we're going to be there as shelter from the storm."

Source: http://news.yahoo.com/blogs/ticket/consoler-chief-obama-tragedy-speeches-142928364.html

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Samsung set to open research center in Finland, Nokia's home ground

DNP Samsung to open research center in Finland, Nokia's home ground

Earlier today, we learned that Samsung had bested Nokia on its home turf by claiming the lion's share of phone sales in Finland last quarter, but its invasion of Nokia's territory won't end there. Samsung will soon unveil a new research hub in Espoo, Finland, and a company rep confirmed that the center will open its doors on June 13th. Though specifics about the nature of research are being kept under wraps, a recent job posting from Oikotie revealed what could be the center's name: Samsung Electronics Research Institute. SERI could potentially be related to Samsung's partnership with Finland's VTT Technical Research Center, announced last month, to explore energy efficient technologies. Beyond that, details are sparse, but we'll keep you posted as more information on Samsung's latest R&D endeavor trickles in.

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Source: http://www.engadget.com/2013/05/28/samsung-finland-research-center/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Tuesday, May 28, 2013

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    Emoticons

    "); // Add smilies into the mix ipb.editor_values.set( 'show_emoticon_link', false ); ipb.editor_values.set( 'bbcodes', $H({"snapback":{"id":"1","title":"Post Snap Back","desc":"This tag displays a little linked image which links back to a post - used when quoting posts from the board. 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    1 Replies - 28 Views - Last Post: Today, 01:40 PM

    #1 noja190 ?Icon User is offline

    Reputation: 0

    • Posts: 22
    • Joined: 30-May 12

    Posted Today, 01:35 PM

    End of the school year is almost here, and me and my friend want to dedicate the summer to learning C++

    I've always wondered though. On big programming projects like games and firewall programs, How do multiple people work together on code? I'd imagine it would get very messy.

    Anyways...I'm using CodeBlocks right now, but is there another IDE that will let you program together in real-time?

    If not, How can we work together on programming?

    This post has been edited by noja190: Today, 01:35 PM


    Is This A Good Question/Topic? 0

    Replies To: Question: Real time Co-Op programming?

    #2 modi123_1 ?Icon User is online

    Reputation: 6492

    • Posts: 23,597
    • Joined: 12-June 08

    Re: Question: Real time Co-Op programming?

    Posted Today, 01:40 PM

    Quote

    I've always wondered though. On big programming projects like games and firewall programs, How do multiple people work together on code? I'd imagine it would get very messy.


    Two things - planning and source control.

    Quote

    Anyways...I'm using CodeBlocks right now, but is there another IDE that will let you program together in real-time?


    I would hope not. That would be.. odd. Pair programming - where you have one person driving and the other looking over their shoulder - bugs me enough I couldn't imagine trying to code around what ever someone is editing the same file you are using.

    Quote

    If not, How can we work together on programming?


    You take your project.. and before you even touch a lick of code you plan. Break it down into manageable pieces, logical parts, set milestones, etc. Then you dole those work chunks out to people. They key is everyone works off the same code repository - be it Team Foundation Server, GITHUB, SVN, etc. Then as people get chunks done you have someone (or that person) integrate that into the code repository and everyone gets a new copy and continues working. It's like building things with legos. Small pieces make up the bigger pieces makes up the Death Star. You know - the whole 'object orientated programming' method.

    Page 1 of 1


    Source: http://www.dreamincode.net/forums/topic/321930-question-real-time-co-op-programming/

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    Reporter Hit by Baseball, Carries on Like a Pro

    Source: http://www.thehollywoodgossip.com/2013/05/reporter-hit-by-baseball-carries-on-like-a-pro/

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    Monday, May 27, 2013

    Scientists cast doubt on Alzheimer's cancer drug study | The Raw Story

    By Agence France-Presse
    Sunday, May 26, 2013 9:01 EDT

    ?

    Like Raw Story on Facebook

    Four separate teams of scientists have said they were unable to replicate a highly publicized study that last year touted a cancer drug?s success against Alzheimer?s disease in mice.

    ?We wanted to repeat the study to see if we could build on it, and we couldn?t,? said David Borchelt, a professor of neuroscience at the University of Florida, noting that ?it was important to publish the fact.?

    ?Maybe there should be some caution going forward in regard to patients,? he added.

    The high profile 2012 study in the US journal Science found that mice treated with bexarotene became rapidly smarter and the plaque in their brains that was causing Alzheimer?s started to disappear within hours.

    The drug was believed to work by boosting levels of a protein, Apolipoprotein E (ApoE), that helps clear amyloid plaque buildup in the brain, a key hallmark of Alzheimer?s disease.

    ?We were shocked and amazed,? lead author Gary Landreth, a professor in the Department of Neurosciences at Case Western Reserve University School of Medicine in Ohio, told AFP when the study was published in February 2012.

    ?Things like this had never, ever been seen before,? he said.

    But a key part of science is being able to replicate the findings of any research, and international researchers reported in four separate papers in Science?s May 24 edition that they had failed to do so.

    Other researchers who published their attempts were Bart De Strooper, director of the VIB Center for the Biology of Disease in Belgium, and Sangram Sisodia, director of the Center for Molecular Neurobiology at the University of Chicago.

    The scientists said their studies showed no effect on the plaque levels in three different populations of lab mice treated with bexarotene.

    A fourth group of researchers said they observed mental gains in the mice but could not confirm they were achieved by the mechanism initially reported, said co-author Iliya Lefterov, associate professor at the University of Pittsburgh Graduate School of Public Health.

    ?While we were able to verify that the mice quickly regained their lost cognitive skills and confirmed the decrease in amyloid beta peptides in the interstitial fluid that surrounds brain cells, we did not find any evidence that the drug cleared the plaques from their brains.?

    The findings should also serve as a warning for doctors not to prescribe bexarotene as an off-label treatment for Alzheimer?s, researchers said.

    The drug, also known as Targretin, was approved by the US Food and Drug Administration in 1999 for treating a type of skin cancer known as refractory cutaneous T-cell lymphoma.

    ?Anecdotally, we have all heard that physicians are treating their Alzheimer?s patients with bexarotene, a cancer drug with severe side effects,? said Robert Vassar, professor of cell and molecular biology at Northwestern University Feinberg School of Medicine.

    ?This practice should be ended immediately, given the failure of three independent research groups to replicate the plaque-lowering effects of bexarotene.?

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    Source: http://www.rawstory.com/rs/2013/05/26/scientists-cast-doubt-on-alzheimers-cancer-drug-study/

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    Your Internet Marketing Plan and Your Business Future ? Hot Article ...

    Internet marketing can turn out to be very difficult to do. The outcome that you expect is not really important when it comes to your online business, but you should not start your business without a plan. The kinds of internet marketing strategies that you want to use is not important. Be certain that you have a plan for all of your techniques. However, there may be a question that you want to ask. So what do you need to do to plan the internet marketing for your business? How do you see to it that you?re headed in the right direction? The following article talks about three useful tips that you can use right away to improve your online marketing plan.

    There are several Internet marketing strategies that you can work with. However, when you create a personal IM plan, make sure that it is something that you don?t have a problem doing. You have to select your methods according to the things that you want to happen in the end. Also, base your decision on the time you have on hand and the goals you have to achieve. For example, think about using PPC marketing if you have to have a fast outcome. However, if you can put a lot of effort into it, then you should consider use SEO as your key strategy.

    If your business is typical, then there will come a time when you have to improvise so do not worry about it.

    Anytime something comes up that is different in some way, then you just have to assess it and make your choices. Later on you will add marketing and advertising that you were not aware of when first creating your plan. Once completed, then immediately begin working on implementing what you want to do according to the plan. Even if something has to be changed, then you can do that on the fly and move forward.

    Do not leave out your website from your IM plan. You will need this for your total IM plan. So, see to it that it?s got all the important elements in it. Plan the design, content and placement of your subscription box, etc. Be certain that your website does not have any overlooked components. The only way that you can accomplish this is by using a good plan. Also, jot down what type of software is needed. This lets your plan and stay on track. It is hard to beat the benefits of building your business plan based on your own specific goals. As you move ahead and work your way up the ladder, you will achieve this much needed clarity. But without everything planned out well in advance, it?s really not possible to reach the heights of Internet marketing success. The most important thing is to have something to work from and follow in the very beginning.

    James Steele is a well-known blogger who writes informative articles on different topics such as marketing, online business, home business, network marketing etc. Checkout his article on My Video Talk review and on Ambit review

    Source: http://hotarticledepot.com/your-internet-marketing-plan-and-your-business-future/

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    GOP continues to slam new Obama war approach

    WASHINGTON (AP) ? Republicans keep slamming President Barack Obama's push to move the government away from a war footing and refine and recalibrate counterterrorism strategy.

    Capitol Hill Republicans like Sen. Lindsey Graham of South Carolina say Obama is projecting weakness at a time when the United States needs to show resolve against terror networks like al-Qaida.

    The South Carolina Republican said Sunday that "at a time when we need resolve the most, we're sounding retreat."

    Obama gave a major speech Thursday in which he said al-Qaida is "on the path to defeat" and he's signaling that he's reluctant to commit troops overseas to conflicts like Syria or other countries struggling with instability in the uncertain aftermath of the Arab Spring. He's also modifying policies on the use of unmanned drone aircraft to try to limit civilian casualties and is redoubling his longstanding ? but so far unfulfilled ? promise to close the prison at Guantanamo Bay, Cuba, where many terrorism suspects are being held without formal charges.

    Obama is trying to recast the image of terrorists from enemy warriors to cowardly thugs and move the United States away a state of perpetual war.

    But Graham said Obama is displaying a "lack of resolve" despite a slew of concerns in the Middle East, including civil war and chemical weapons in Syria and threats to Israel from Syria's unrest and Iran's nuclear program.

    "We show this lack of resolve, talking about the war being over," Graham said. "What do you think the Iranians are thinking? At the end of the day, this is the most tone-deaf president I ever could imagine."

    "I see a big difference between the president saying the war's at an end and whether or not you've won the war," said Sen. Tom Coburn, R-Okla. "We can claim that it's at an end, but this war's going to continue. And we have still tremendous threats out there, that are building, not declining, building, and to not recognize that, I think, is dangerous in the long run and dangerous for the world."

    Sen. Dick Durbin, D-Ill., defended the president, reprising Obama's theme that maintaining a wartime posture runs the risk of compromising U.S. principles.

    "If we're constantly thinking of this as a war, we stand a chance of doing things that compromise our freedoms," Durbin said.

    Obama ally Sen. Charles Schumer, D-N.Y., said that "having transparency, having rules and engaging other activities other than military to help curb the war on terror ? diplomacy, economic sanctions and things like that ? is going to be useful as well. So I think the president did a very, very smart pivot, realizing we're not going to let up on terrorists, but at the same time we're going to meet the changes in the world."

    Graham and Durbin spoke on "Fox News Sunday." Schumer and Coburn spoke on CBS' "Face the Nation."

    Source: http://news.yahoo.com/gop-continues-slam-obama-war-approach-143429204.html

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    Sunday, May 26, 2013

    Boston Marathon Runners Finish At Indianapolis 500

    INDIANAPOLIS -- Bundled up against the cold and with tears in their eyes, dozens of runners unable to complete the Boston Marathon due to the bombings last month finally finished their runs over the famed yard of bricks at Indianapolis Motor Speedway on Sunday.

    The runners were honored at the Indianapolis 500 by having the opportunity to run down the front stretch moments before to the "Greatest Spectacle in Racing." Thousands of people, including some crew members of the race teams, cheered them on as they ran down pit road.

    Jennifer Black, a 61-year-old from Loveland, Ohio, said she ran to the finish line with tears in her eyes after she saw her husband waving to her from the track's fourth turn.

    "I was crying while I was running and blowing kisses to the crowd," she said.

    The group crossed the finish line flanked by firefighters and police officers, breaking the tape less than 10 minutes before the command was given to start the engines.

    "It was incredible. I have never run through a crowd like this," said Amber Larason of Nashville, Tenn., who was running the Boston Marathon with her mom and about two miles from the finish line on Boylston Street when the bombs exploded on April 15.

    "I've never experienced anything like this," Larason said. "It was amazing."

    All the runners who participated Sunday were pulled off the Boston Marathon course by officials after the bombings, which killed three people and wounded more than 250. Speedway officials extended an invitation to finish to the Boston Athletic Association, which contacted runners from Indiana and nearby states.

    "The tragedy last month in Boston still resonates with everyone, so we wanted to give runners the chance to finish the race in front of thousands of fans who will appreciate their persistence and determination," said Doug Boles, the speedway's chief operating officer.

    Black was wearing her Boston numerical marker with the number "21015" pinned to the top of her running jersey. She was about a half-mile from the finish when the bombs went off at the marathon, and remembers thinking medics were rushing to aid a runner who suffered a heart attack. When she learned it was a bomb, Black said she feared that her sister, former Rep. Jean Schmidt, R-Ohio, might have been injured. Schmidt was waiting near the finish line, uninjured.

    On Sunday, Schmidt waited again for her sister as she crossed the finish line, this time at the speedway. Schmidt urged people to donate to a fund established for victims of the bombing ? onefundboston.org.

    "These people need our help. There will be no government help like there will be for the people in Moore, Okla.," she said. "There will be no government aid to these people. These people have an economic loss as well as limbs lost ? life lost, lives permanently damaged."

    Ron Kuczma, a 65-year-old from Hudson, Ohio, said it was thrilling to be able to take part in a ceremonial finish at the speedway, where several fans waved American flags.

    But Kuczma said he couldn't help thinking about the families of the bombing victims and the runners who are still recovering.

    "We're here having a lot of fun today. We were treated like dignitaries," he said, "but there were a lot of people who were hurt in the bombings. And people died. We ran for them today. They couldn't be here and we could so we ran for them."

    Paul Ryan of Marlborough, Mass., brought his father and sons to the race from the Boston area, and was unaware that the speedway was honoring victims of the bombing.

    "I think it's great that they were bringing people out here to honor and still to keep it going because people forget stuff so fast these days. It's great that they were acknowledged out here," he said. "There's a lot of awful things going on right now that it's easy to lose focus.

    "We just appreciate it, being from Boston, that other people notice it."

    ___

    Associated Press writer Rick Callahan and AP freelance writer Jim Johnson contributed to this report.

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    Source: http://www.huffingtonpost.com/2013/05/26/boston-marathon-runners-indianapolis-500-finish_n_3339850.html

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    French police search for man who stabbed soldier

    Police officers stand near the cordoned off spot where a French soldier was stabbed in the throat in the busy commercial district of La Defense, outside Paris, Saturday May 25, 2013, and France's president said authorities are investigating any possible links with the recent slaying of a British soldier.(AP Photo/Remy de la Mauviniere)

    Police officers stand near the cordoned off spot where a French soldier was stabbed in the throat in the busy commercial district of La Defense, outside Paris, Saturday May 25, 2013, and France's president said authorities are investigating any possible links with the recent slaying of a British soldier.(AP Photo/Remy de la Mauviniere)

    Police officers stand near the cordoned off spot where a French soldier was stabbed in the throat in the busy commercial district of La Defense, outside Paris, Saturday May 25, 2013, and France's president said authorities are investigating any possible links with the recent slaying of a British soldier.(AP Photo/Remy de la Mauviniere)

    Police officers stand near the cordoned off spot where a French soldier was stabbed in the throat in the busy commercial district of La Defense, outside Paris, Saturday May 25, 2013, and France's president said authorities are investigating any possible links with the recent slaying of a British soldier.(AP Photo/Remy de la Mauviniere)

    PARIS (AP) ? French anti-terrorism investigators were combing video surveillance tapes Sunday as they continued their manhunt for a suspect who stabbed a soldier in the throat in the commercial district of La Defense outside Paris.

    The 23-year-old soldier, Cedric Cordier, was in uniform patrolling the busy underground corridors where shops and crowded public transport lines converge beneath the famous Arch of La Defense.

    Saturday's stabbing came days after a British soldier was hacked to death on a London street in broad daylight in a suspected terrorist attack that has raised fears of potential copycat strikes. However, there was no immediate confirmation of any link between the two attacks.

    French police have surveillance video of a suspect taken before and after the attack. There are several security cameras operated by public transport agency RATP and others placed throughout the underground shopping center, according to one police official who spoke on condition of anonymity because he wasn't authorized to discuss terrorism investigations.

    The official, who has not seen the videos himself, said investigators describe the suspect as tall. He couldn't provide any other description of the suspect. Police are going over videos to try to identify the suspect, trace his escape route and determine whether he was acting alone, the official said.

    Cordier remained hospitalized Sunday, but officials said his throat wound wasn't life-threatening.

    The French soldier was on a group patrol as part of a national protection program when he was attacked from behind.

    Defense Minister Jean-Yves Le Drian, who visited Cordier at the hospital Saturday evening, said he had been targeted because he was a soldier. Anti-terrorism investigators are leading the hunt for the attacker, but officials have yet to determine whether terrorism is involved, the police official said. Police also questioned witnesses to the attack.

    Speaking shortly after the attack while on an official visit to Ethiopia, President Francois Hollande said that while "all hypotheses" will be investigated, there didn't appear to be a link with Wednesday's deadly attack in London.

    French security forces have been on heightened alert since their country launched a military intervention in the African nation of Mali in January to regain territory seized by Islamic radicals. British Prime Minister David Cameron was in Paris meeting with Hollande when he first received word of the London attack.

    Last year, three French paratroopers were killed by a man police described as a French-born Islamic extremist who then went on to strike a Jewish school in southern France, killing four more people.

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-05-26-EU-France-Soldier-Stabbed/id-511c5236a29f445caf6e1b6f903c301c

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    Cyclist tests positive for EPO, risks life ban

    ROME (AP) ? Cycling's first major race since the end of the Lance Armstrong case was rattled by another high-profile positive doping test Friday.

    Former Giro d'Italia winner Danilo Di Luca tested positive for EPO in a surprise check at his home before this year's race, organizers said.

    If confirmed in a backup "B'' sample, Di Luca risks a lifetime ban since this is his third offense.

    "I wasn't expecting this. It was a surprise for me. I'm disappointed," Di Luca said upon leaving his team's hotel in northern Italy. "I'll ask for the backup analysis, then we can talk again."

    Armstrong appeared surprised, too.

    "Knowing I have 0 cred on the doping issue - I still can't help but think, 'really Di Luca? Are you that ... stupid??" Armstrong tweeted, adding an expletive.

    It's the second doping case from this year's Giro, after French rider Sylvain Georges tested positive for the banned stimulant Heptaminol in a urine sample after the seventh stage. The 28-year-old AG2R La Mondiale rider was immediately withdrawn from the race.

    The UCI provisionally suspended Di Luca pending a hearing with the Italian cycling federation and the Vini Fantini-Selle Italia team fired the 37-year-old Italian rider.

    "Danilo has betrayed cycling once again," Giro race director Mauro Vegni said. "But I'm happy it wasn't a young rider. Danilo belongs to a generation that has navigated through the doping system."

    After being stripped of his seven Tour de France titles, Armstrong confessed to doping in a TV interview in January with Oprah Winfrey. While many of Armstrong's former teammates have come forward to say they doped, some of the riders who supported the Texan during his career continue to race.

    Longtime Armstrong lieutenant Yaroslav Popovych, a Ukrainian rider with the RadioShack-Leopard team, is 139th overall in the Giro.

    The test on Di Luca was carried out April 29, five days before the Giro started, and the result drew a rebuke from Vini Fantini team director Luca Scinto.

    "Di Luca is an idiot. I never wanted him," Scinto said. "Di Luca is sick. He needs to be helped."

    Seemingly headed for retirement just a few months ago, Di Luca signed with Vini Fantini on April 26. Scinto and others were against hiring him, but sponsors eventually prevailed.

    "The sponsors chose him and now they've got to take responsibility," Scinto said.

    The team is considering suing Di Luca for damaging its image.

    The race ends Sunday and Di Luca departs in 26th place overall, 33 minutes, 33 seconds behind overall leader Vincenzo Nibali.

    The announcement came a day after the 28-year-old Nibali extended his lead by dominating a mountain time trial, garnering headlines in Italy as the new face of the sport.

    In 2009, Di Luca was given a two-year ban after testing positive during the Giro for CERA, an advanced form of the blood booster EPO. That ban was subsequently reduced by nine months after he collaborated with Italian anti-doping authorities.

    And after winning the 2007 Giro, Di Luca was banned for three months later in the year for frequent visits to Carlo Santuccione, a physician at the center of a four-year doping investigation titled Oil for Drugs.

    Di Luca was stripped of his second-place finish and two stage wins in the 2009 Giro, which was won by Denis Menchov, a Russian rider who was never banned for doping but was often linked to banned drug cases.

    Armstrong raced the Giro for the only time in 2009, but did not contend for the title.

    Di Luca fared well in several stages of this year's Giro, finishing third in the seventh leg, seventh in Stage 9, sixth in Stage 11 and 10th in Thursday's uphill time trial.

    "He wrote me a text message saying, 'I don't know what to say. I'm sorry,'" Giro director Michele Acquarone said. "If someone looks you in the eye and asks for your support and then betrays you, then it means he has a serious problem ? in this case a strong addiction."

    The Giro's 19th stage on Friday was canceled because of snow.

    Source: http://news.yahoo.com/cyclist-tests-positive-epo-risks-life-ban-124923801.html

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    Saturday, May 25, 2013

    Bridge collapses in Washington state ? cars, people in water

    Taylor Linden

    Cars and people are in the Skagit River at the scene of an I-5 bridge collapse near Mt. Veron, Wash.

    By Andrew Rafferty and Justin Kirschner, NBC News

    Three people were rescued from a river after a bridge along Interstate-5 in Washington State collapsed on Thursday evening, plunging cars into the water below, according to Washington State Patrol.

    MSNBC's Milissa Rehberger reports that people and cars were in the water after an I-5 bridge collapsed over the Skagit River in Washington state.

    The extent of the injuries for the three is unclear, but all were evaluated on scene and were transported to area hospitals, according to Marcus Deyerin of the Washington Incident Management Team. Authorities say they have no reason to believe any others are still in the river.

    Two vehicles were submerged in the Skagit River when the bridge fell around 7 p.m. local time (10 p.m. EDT), and traffic has been closed in both directions.

    NBC Seattle affiliate KING5 reported that traffic was significantly backed up in both directions. I-5 is the main freeway that runs along the West Coast.

    A witnesses told KING5 that an oversized truck hit the upper right side of the bridge before the collapse, though it wasn't clear if that caused the span to give way.

    The minimum vertical clearance on the bridge (distance from the road to something a truck can bump into) is 14.5 feet. The standard height is 16 feet.

    This I-5 bridge over the Skagit River at Mount Vernon was described by the Washington State Department of Transportation, after an inspection in August 2010, as "somewhat better than minimum adequacy to tolerate being left in place as is."

    State inspection reports submitted to the Federal Highway Administration were reviewed by NBC News. That overall evaluation of the structural condition on the bridge corresponds to a score of 5 on a scale from 0 (worst) to 9 (best).

    The bridge received identical scores on inspections in 2010, 2008 and 2006, and is on a schedule for inspection every 24 months, as generally required by federal regulations. State officials said Thursday evening they were working to make public a copy of the latest inspection report, presumably from 2012.

    Looking at specific areas of the bridge, the substructure (piers, abutments, footings, piles, etc.) was described as in satisfactory condition, with the superstructure (beams, girders, stringers, trusses, cables, pins, hangers, etc.) in somewhat worse condition, listed as fair, according to the inspection data online from the Federal Highway Administration. "Fair" meant that all primary structural elements were sound but may have minor defects.

    The 1,112-foot steel truss bridge was built in 1955, and was carrying an average daily traffic of 71,000 vehicles.

    The bridge was of a "fracture critical" design, as are 18,000 bridges nationwide, meaning it could collapse if even one part failed.

    Even after the bridge collapse that killed 13 people in Minneapolis in 2007, a haphazard system of inspections continued, with federal authorities choosing not to require re-inspection of all the fracture-critical bridges.

    In a survey of every state by msnbc.com in 2008, only six states and the District of Columbia said they began to recheck all their fracture-critical bridges.

    Officials in Washington state, like in most states, said they performed special inspections of only their few dozen bridges of the particular deck-truss design used in Minneapolis.

    The bridge that fell Thursday did go on to receive its regular inspections in 2008 and 2010, according to the federal records, called the National Bridge Inventory.

    Bill Dedman of NBC News contributed to this report.

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    Gina Cole / Skagit Valley Herald

    North end of the I-5 bridge over Skagit River collapsed Thursday night.

    Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2c5591eb/l/0Lusnews0Bnbcnews0N0C0Inews0C20A130C0A50C240C184560A810Ebridge0Ecollapses0Ein0Ewashington0Estate0Ecars0Epeople0Ein0Ewater0Dlite/story01.htm

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